Population-Based External Validation of the EASIX Scores to Predict CAR T-Cell-Related Toxicities

Population-Based External Validation of the EASIX Scores to Predict CAR T-Cell-Related Toxicities

Cytokine release syndrome (CRS) and immune effector cell-associated neurotoxicity syndrome (ICANS) can hamper the clinical benefit of CAR T-cell therapy in patients with relapsed/refractory large B-cell lymphoma (r/r LBCL). To assess the risk of CRS and ICANS, the endothelial activation and stress i...

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Bibliographic Details
Main Authors: Janneke W. de Boer, Kylie Keijzer, Elise R. A. Pennings, Jaap A. van Doesum, Anne M. Spanjaart, Margot Jak, Pim G. N. J. Mutsaers, Suzanne van Dorp, Joost S. P. Vermaat, Marjolein W. M. van der Poel, Lisanne V. van Dijk, Marie José Kersten, Anne G. H. Niezink, Tom van Meerten
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Cancers
Subjects:
CAR T-cell therapy
toxicity
EASIX
LBCL
Online Access:https://www.mdpi.com/2072-6694/15/22/5443

Internet

https://www.mdpi.com/2072-6694/15/22/5443

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