Current State of Knowledge about Role of Pets in Zoonotic Transmission of SARS-CoV-2
Pets play a crucial role in the development of human feelings, social life, and care. However, in the era of the prevailing global pandemic of COVID-19 disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), many questions addressing the routes of the virus spread and tra...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-06-01
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| Series: | Viruses |
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| Online Access: | https://www.mdpi.com/1999-4915/13/6/1149 |
| _version_ | 1797529948488990720 |
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| author | Mateusz Dróżdż Paweł Krzyżek Barbara Dudek Sebastian Makuch Adriana Janczura Emil Paluch |
| author_facet | Mateusz Dróżdż Paweł Krzyżek Barbara Dudek Sebastian Makuch Adriana Janczura Emil Paluch |
| author_sort | Mateusz Dróżdż |
| collection | DOAJ |
| description | Pets play a crucial role in the development of human feelings, social life, and care. However, in the era of the prevailing global pandemic of COVID-19 disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), many questions addressing the routes of the virus spread and transmission to humans are dramatically emerging. Although cases of SARS-CoV-2 infection have been found in pets including dogs, cats, and ferrets, to date there is no strong evidence for pet-to-human transmission or sustained pet-to-pet transmission of SARS-CoV-2. However, an increasing number of studies reporting detection of SARS-CoV-2 in farmed minks raises suspicion of potential viral transmission from these animals to humans. Furthermore, due to the high susceptibility of cats, ferrets, minks and hamsters to COVID-19 infection under natural and/or experimental conditions, these animals have been extensively explored as animal models to study the SARS-CoV-2 pathogenesis and transmission. In this review, we present the latest reports focusing on SARS-CoV-2 detection, isolation, and characterization in pets. Moreover, based on the current literature, we document studies aiming to broaden the knowledge about pathogenicity and transmissibility of SARS-CoV-2, and the development of viral therapeutics, drugs and vaccines. Lastly, considering the high rate of SARS-CoV-2 evolution and replication, we also suggest routes of protection against the virus. |
| first_indexed | 2024-03-10T10:22:08Z |
| format | Article |
| id | doaj.art-0f7a767dcb7249e1bf079d70c4c793ca |
| institution | Directory Open Access Journal |
| issn | 1999-4915 |
| language | English |
| last_indexed | 2024-03-10T10:22:08Z |
| publishDate | 2021-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Viruses |
| spelling | doaj.art-0f7a767dcb7249e1bf079d70c4c793ca2023-11-22T00:18:51ZengMDPI AGViruses1999-49152021-06-01136114910.3390/v13061149Current State of Knowledge about Role of Pets in Zoonotic Transmission of SARS-CoV-2Mateusz Dróżdż0Paweł Krzyżek1Barbara Dudek2Sebastian Makuch3Adriana Janczura4Emil Paluch5Laboratory of RNA Biochemistry, Institute of Chemistry and Biochemistry, Freie Universität Berlin, Takustraße 6, 14195 Berlin, GermanyDepartment of Microbiology, Wrocław Medical University, St. T. Chałubińskiego 4, 50-376 Wrocław, PolandLaboratory of Microbiology, Private Health Care Institution, St. Jana Pawła II, 41-100 Siemianowice Śląskie, PolandDepartment of Pathology, Wrocław Medical University, St. K. Marcinkowskiego 1, 50-368 Wrocław, PolandDepartment of Microbiology, Wrocław Medical University, St. T. Chałubińskiego 4, 50-376 Wrocław, PolandDepartment of Microbiology, Wrocław Medical University, St. T. Chałubińskiego 4, 50-376 Wrocław, PolandPets play a crucial role in the development of human feelings, social life, and care. However, in the era of the prevailing global pandemic of COVID-19 disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), many questions addressing the routes of the virus spread and transmission to humans are dramatically emerging. Although cases of SARS-CoV-2 infection have been found in pets including dogs, cats, and ferrets, to date there is no strong evidence for pet-to-human transmission or sustained pet-to-pet transmission of SARS-CoV-2. However, an increasing number of studies reporting detection of SARS-CoV-2 in farmed minks raises suspicion of potential viral transmission from these animals to humans. Furthermore, due to the high susceptibility of cats, ferrets, minks and hamsters to COVID-19 infection under natural and/or experimental conditions, these animals have been extensively explored as animal models to study the SARS-CoV-2 pathogenesis and transmission. In this review, we present the latest reports focusing on SARS-CoV-2 detection, isolation, and characterization in pets. Moreover, based on the current literature, we document studies aiming to broaden the knowledge about pathogenicity and transmissibility of SARS-CoV-2, and the development of viral therapeutics, drugs and vaccines. Lastly, considering the high rate of SARS-CoV-2 evolution and replication, we also suggest routes of protection against the virus.https://www.mdpi.com/1999-4915/13/6/1149SARS-CoV-2COVID-19pets suitable animal modelszoonotic potential |
| spellingShingle | Mateusz Dróżdż Paweł Krzyżek Barbara Dudek Sebastian Makuch Adriana Janczura Emil Paluch Current State of Knowledge about Role of Pets in Zoonotic Transmission of SARS-CoV-2 Viruses SARS-CoV-2 COVID-19 pets suitable animal models zoonotic potential |
| title | Current State of Knowledge about Role of Pets in Zoonotic Transmission of SARS-CoV-2 |
| title_full | Current State of Knowledge about Role of Pets in Zoonotic Transmission of SARS-CoV-2 |
| title_fullStr | Current State of Knowledge about Role of Pets in Zoonotic Transmission of SARS-CoV-2 |
| title_full_unstemmed | Current State of Knowledge about Role of Pets in Zoonotic Transmission of SARS-CoV-2 |
| title_short | Current State of Knowledge about Role of Pets in Zoonotic Transmission of SARS-CoV-2 |
| title_sort | current state of knowledge about role of pets in zoonotic transmission of sars cov 2 |
| topic | SARS-CoV-2 COVID-19 pets suitable animal models zoonotic potential |
| url | https://www.mdpi.com/1999-4915/13/6/1149 |
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