Optimizing Conditions to Cholesterol Adsorbed with Carboxymethyl Chitosan

A research on optimizing conditions to cholesterol adsorbed have been performed. Optimization was performed by varying: contact time, adsorbent weight and temperature of the system's. A full factorial experimental design was used in this study. Characterization performed on the synthesized chit...

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Main Authors: Mardiyah Kurniasih, Dwi Kartika, Riyanti Riyanti
Format: Article
Language:English
Published: Jenderal Soedirman University 2016-05-01
Series:Molekul
Subjects:
Online Access:http://ojs.jmolekul.com/ojs/index.php/jm/article/view/200
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author Mardiyah Kurniasih
Dwi Kartika
Riyanti Riyanti
author_facet Mardiyah Kurniasih
Dwi Kartika
Riyanti Riyanti
author_sort Mardiyah Kurniasih
collection DOAJ
description A research on optimizing conditions to cholesterol adsorbed have been performed. Optimization was performed by varying: contact time, adsorbent weight and temperature of the system's. A full factorial experimental design was used in this study. Characterization performed on the synthesized chitosan and carboxymethyl chitosan including FTIR, water content, ash content, solubility, porosity, and swelling effect. The results showed that carboxymethyl chitosan able to adsorb cholesterol under conditions optimal adsorbent with cholesterol ratio (1:200) with a contact time of 90 minutes at temperature of 40 °C. Meanwhile, at a temperature of 55 °C carboxymethyl chitosan capable of adsorb cholesterol under conditions optimal adsorbent with cholesterol ratio (1:300) with a contact time of 30 minutes. Chitosan and carboxymethyl chitosan synthesized has a water content of 7.4 and 10.2%, ash content of 0.14 and 2.29%, solubility in distilled water at 1.10-5and 1.98.10-3%, solubility in acetic acid 0.02 and 0.04%, porosity at 88.3% and 88.8%, and swelling at 163.13 and 182.98%.
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spelling doaj.art-0f7b49f2ca48492f8e85b448377b02832022-12-21T18:29:59ZengJenderal Soedirman UniversityMolekul1907-97612503-03102016-05-0111111212410.20884/1.jm.2016.11.1.200193Optimizing Conditions to Cholesterol Adsorbed with Carboxymethyl ChitosanMardiyah KurniasihDwi KartikaRiyanti RiyantiA research on optimizing conditions to cholesterol adsorbed have been performed. Optimization was performed by varying: contact time, adsorbent weight and temperature of the system's. A full factorial experimental design was used in this study. Characterization performed on the synthesized chitosan and carboxymethyl chitosan including FTIR, water content, ash content, solubility, porosity, and swelling effect. The results showed that carboxymethyl chitosan able to adsorb cholesterol under conditions optimal adsorbent with cholesterol ratio (1:200) with a contact time of 90 minutes at temperature of 40 °C. Meanwhile, at a temperature of 55 °C carboxymethyl chitosan capable of adsorb cholesterol under conditions optimal adsorbent with cholesterol ratio (1:300) with a contact time of 30 minutes. Chitosan and carboxymethyl chitosan synthesized has a water content of 7.4 and 10.2%, ash content of 0.14 and 2.29%, solubility in distilled water at 1.10-5and 1.98.10-3%, solubility in acetic acid 0.02 and 0.04%, porosity at 88.3% and 88.8%, and swelling at 163.13 and 182.98%.http://ojs.jmolekul.com/ojs/index.php/jm/article/view/200adsorption, carboxymethyl chitosan, characterization, cholesterol
spellingShingle Mardiyah Kurniasih
Dwi Kartika
Riyanti Riyanti
Optimizing Conditions to Cholesterol Adsorbed with Carboxymethyl Chitosan
Molekul
adsorption, carboxymethyl chitosan, characterization, cholesterol
title Optimizing Conditions to Cholesterol Adsorbed with Carboxymethyl Chitosan
title_full Optimizing Conditions to Cholesterol Adsorbed with Carboxymethyl Chitosan
title_fullStr Optimizing Conditions to Cholesterol Adsorbed with Carboxymethyl Chitosan
title_full_unstemmed Optimizing Conditions to Cholesterol Adsorbed with Carboxymethyl Chitosan
title_short Optimizing Conditions to Cholesterol Adsorbed with Carboxymethyl Chitosan
title_sort optimizing conditions to cholesterol adsorbed with carboxymethyl chitosan
topic adsorption, carboxymethyl chitosan, characterization, cholesterol
url http://ojs.jmolekul.com/ojs/index.php/jm/article/view/200
work_keys_str_mv AT mardiyahkurniasih optimizingconditionstocholesteroladsorbedwithcarboxymethylchitosan
AT dwikartika optimizingconditionstocholesteroladsorbedwithcarboxymethylchitosan
AT riyantiriyanti optimizingconditionstocholesteroladsorbedwithcarboxymethylchitosan