Ibogaine-Mediated ROS/Antioxidant Elevation in Isolated Rat Uterus Is β-Adrenergic Receptors and K<sub>ATP</sub> Channels Mediated

Ibogaine-Mediated ROS/Antioxidant Elevation in Isolated Rat Uterus Is β-Adrenergic Receptors and K<sub>ATP</sub> Channels Mediated

Ibogaine effects are mediated by cellular receptors, ATP depletion followed by ROS production and antioxidant enzyme activity elevation in a dose and time dependent manner. Since the role of K<sub>ATP</sub> channels and β-adrenoceptors in ROS cellular circuit was established here we expl...

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Bibliographic Details
Main Authors: Nikola Tatalović, Teodora Vidonja Uzelac, Zorana Oreščanin Dušić, Aleksandra Nikolić-Kokić, Mara Bresjanac, Duško Blagojević
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Antioxidants
Subjects:
ibogaine
K<sub>ATP</sub> channels
glibenclamide
β-adrenergic receptors
propranolol
antioxidative enzymes
Online Access:https://www.mdpi.com/2076-3921/10/11/1792

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