Infection characteristics of porcine circovirus type 2 in different herds from intensive farms in China, 2022
IntroductionPorcine circovirus type 2 (PCV2) is the primary etiological agent of porcine circovirus diseases (PCVD), which are widespread in most pig herds, causing huge economic losses in the global pig industry. Therefore, it is critical to assess the infection characteristics of PCV2 in different...
| Main Authors: | , , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2023-06-01
|
| Series: | Frontiers in Veterinary Science |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fvets.2023.1187753/full |
| _version_ | 1797803706106773504 |
|---|---|
| author | Mingyu Fan Mingyu Fan Lujie Bian Xiaogang Tian Zhiqiang Hu Weisheng Wu Leilei Sun Guiqiang Yuan Shuangxi Li Lei Yue Ying Wang Lili Wu Yongquan Wang Zheng Yan Jing Ren Xiaowen Li Xiaowen Li Xiaowen Li Xiaowen Li |
| author_facet | Mingyu Fan Mingyu Fan Lujie Bian Xiaogang Tian Zhiqiang Hu Weisheng Wu Leilei Sun Guiqiang Yuan Shuangxi Li Lei Yue Ying Wang Lili Wu Yongquan Wang Zheng Yan Jing Ren Xiaowen Li Xiaowen Li Xiaowen Li Xiaowen Li |
| author_sort | Mingyu Fan |
| collection | DOAJ |
| description | IntroductionPorcine circovirus type 2 (PCV2) is the primary etiological agent of porcine circovirus diseases (PCVD), which are widespread in most pig herds, causing huge economic losses in the global pig industry. Therefore, it is critical to assess the infection characteristics of PCV2 in different swine herds to develop effective strategies against PCVD.MethodsIn this study, routine diagnostic and monitoring protocols were used to collect 12,714 samples from intensive farms in China, and PCV2 was tested for by qPCR to determine positivity rates and viral loads in samples from different herds and materials.ResultsPCV2 was found to be prevalent throughout China, and fattening farms had higher positivity rates than breeding farms. The PCV2 positivity rates in breeding farms in Southern China were higher than those in Northern China. Growing–finishing pigs demonstrated the highest positivity rate in the tested samples, while pre-weaning piglets and adult sows had the lowest. Meanwhile, samples with viral loads exceeding 106 copies/mL in growing–finishing pigs had 27.2% positivity, compared to 1.9% and 3.3% in sows and piglets, respectively. The results of the viral loads in the serum samples followed a similar trend.DiscussionThe findings reveal that PCV2 circulates in different herds from intensive farms, with positivity increasing from pre-weaning to growing–finishing herds. It is urgent to develop effective strategies to reduce PCV2 positivity in growing–finishing herds and prevent viral circulation among pigs. |
| first_indexed | 2024-03-13T05:26:04Z |
| format | Article |
| id | doaj.art-0f7c6cccfe9b43c498d598880de3b3d9 |
| institution | Directory Open Access Journal |
| issn | 2297-1769 |
| language | English |
| last_indexed | 2024-03-13T05:26:04Z |
| publishDate | 2023-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Veterinary Science |
| spelling | doaj.art-0f7c6cccfe9b43c498d598880de3b3d92023-06-15T05:56:44ZengFrontiers Media S.A.Frontiers in Veterinary Science2297-17692023-06-011010.3389/fvets.2023.11877531187753Infection characteristics of porcine circovirus type 2 in different herds from intensive farms in China, 2022Mingyu Fan0Mingyu Fan1Lujie Bian2Xiaogang Tian3Zhiqiang Hu4Weisheng Wu5Leilei Sun6Guiqiang Yuan7Shuangxi Li8Lei Yue9Ying Wang10Lili Wu11Yongquan Wang12Zheng Yan13Jing Ren14Xiaowen Li15Xiaowen Li16Xiaowen Li17Xiaowen Li18Shandong New Hope Liuhe Agriculture and Animal Husbandry Technology Co., Ltd. (NHLH Academy of Swine Research), Dezhou, ChinaShandong Swine Health Data and Intelligent Monitoring Project Laboratory, Dezhou University, Dezhou, ChinaShandong New Hope Liuhe Agriculture and Animal Husbandry Technology Co., Ltd. (NHLH Academy of Swine Research), Dezhou, ChinaShandong New Hope Liuhe Agriculture and Animal Husbandry Technology Co., Ltd. (NHLH Academy of Swine Research), Dezhou, ChinaShandong New Hope Liuhe Agriculture and Animal Husbandry Technology Co., Ltd. (NHLH Academy of Swine Research), Dezhou, ChinaXiajin New Hope Liuhe Agriculture and Animal Husbandry Co., Ltd., Dezhou, ChinaNew Hope Liuhe Co., Ltd., Chengdu, ChinaNew Hope Liuhe Co., Ltd., Chengdu, ChinaNew Hope Liuhe Co., Ltd., Chengdu, ChinaNew Hope Liuhe Co., Ltd., Chengdu, ChinaNew Hope Liuhe Co., Ltd., Chengdu, ChinaShandong New Hope Liuhe Agriculture and Animal Husbandry Technology Co., Ltd. (NHLH Academy of Swine Research), Dezhou, ChinaXiajin New Hope Liuhe Agriculture and Animal Husbandry Co., Ltd., Dezhou, ChinaNew Hope Liuhe Co., Ltd., Chengdu, ChinaShandong Swine Health Data and Intelligent Monitoring Project Laboratory, Dezhou University, Dezhou, ChinaShandong New Hope Liuhe Agriculture and Animal Husbandry Technology Co., Ltd. (NHLH Academy of Swine Research), Dezhou, ChinaShandong Swine Health Data and Intelligent Monitoring Project Laboratory, Dezhou University, Dezhou, ChinaXiajin New Hope Liuhe Agriculture and Animal Husbandry Co., Ltd., Dezhou, ChinaNew Hope Liuhe Co., Ltd., Chengdu, ChinaIntroductionPorcine circovirus type 2 (PCV2) is the primary etiological agent of porcine circovirus diseases (PCVD), which are widespread in most pig herds, causing huge economic losses in the global pig industry. Therefore, it is critical to assess the infection characteristics of PCV2 in different swine herds to develop effective strategies against PCVD.MethodsIn this study, routine diagnostic and monitoring protocols were used to collect 12,714 samples from intensive farms in China, and PCV2 was tested for by qPCR to determine positivity rates and viral loads in samples from different herds and materials.ResultsPCV2 was found to be prevalent throughout China, and fattening farms had higher positivity rates than breeding farms. The PCV2 positivity rates in breeding farms in Southern China were higher than those in Northern China. Growing–finishing pigs demonstrated the highest positivity rate in the tested samples, while pre-weaning piglets and adult sows had the lowest. Meanwhile, samples with viral loads exceeding 106 copies/mL in growing–finishing pigs had 27.2% positivity, compared to 1.9% and 3.3% in sows and piglets, respectively. The results of the viral loads in the serum samples followed a similar trend.DiscussionThe findings reveal that PCV2 circulates in different herds from intensive farms, with positivity increasing from pre-weaning to growing–finishing herds. It is urgent to develop effective strategies to reduce PCV2 positivity in growing–finishing herds and prevent viral circulation among pigs.https://www.frontiersin.org/articles/10.3389/fvets.2023.1187753/fullPCV2pre-weaning pigletnursery piggrowing–finishing piggiltsow |
| spellingShingle | Mingyu Fan Mingyu Fan Lujie Bian Xiaogang Tian Zhiqiang Hu Weisheng Wu Leilei Sun Guiqiang Yuan Shuangxi Li Lei Yue Ying Wang Lili Wu Yongquan Wang Zheng Yan Jing Ren Xiaowen Li Xiaowen Li Xiaowen Li Xiaowen Li Infection characteristics of porcine circovirus type 2 in different herds from intensive farms in China, 2022 Frontiers in Veterinary Science PCV2 pre-weaning piglet nursery pig growing–finishing pig gilt sow |
| title | Infection characteristics of porcine circovirus type 2 in different herds from intensive farms in China, 2022 |
| title_full | Infection characteristics of porcine circovirus type 2 in different herds from intensive farms in China, 2022 |
| title_fullStr | Infection characteristics of porcine circovirus type 2 in different herds from intensive farms in China, 2022 |
| title_full_unstemmed | Infection characteristics of porcine circovirus type 2 in different herds from intensive farms in China, 2022 |
| title_short | Infection characteristics of porcine circovirus type 2 in different herds from intensive farms in China, 2022 |
| title_sort | infection characteristics of porcine circovirus type 2 in different herds from intensive farms in china 2022 |
| topic | PCV2 pre-weaning piglet nursery pig growing–finishing pig gilt sow |
| url | https://www.frontiersin.org/articles/10.3389/fvets.2023.1187753/full |
| work_keys_str_mv | AT mingyufan infectioncharacteristicsofporcinecircovirustype2indifferentherdsfromintensivefarmsinchina2022 AT mingyufan infectioncharacteristicsofporcinecircovirustype2indifferentherdsfromintensivefarmsinchina2022 AT lujiebian infectioncharacteristicsofporcinecircovirustype2indifferentherdsfromintensivefarmsinchina2022 AT xiaogangtian infectioncharacteristicsofporcinecircovirustype2indifferentherdsfromintensivefarmsinchina2022 AT zhiqianghu infectioncharacteristicsofporcinecircovirustype2indifferentherdsfromintensivefarmsinchina2022 AT weishengwu infectioncharacteristicsofporcinecircovirustype2indifferentherdsfromintensivefarmsinchina2022 AT leileisun infectioncharacteristicsofporcinecircovirustype2indifferentherdsfromintensivefarmsinchina2022 AT guiqiangyuan infectioncharacteristicsofporcinecircovirustype2indifferentherdsfromintensivefarmsinchina2022 AT shuangxili infectioncharacteristicsofporcinecircovirustype2indifferentherdsfromintensivefarmsinchina2022 AT leiyue infectioncharacteristicsofporcinecircovirustype2indifferentherdsfromintensivefarmsinchina2022 AT yingwang infectioncharacteristicsofporcinecircovirustype2indifferentherdsfromintensivefarmsinchina2022 AT liliwu infectioncharacteristicsofporcinecircovirustype2indifferentherdsfromintensivefarmsinchina2022 AT yongquanwang infectioncharacteristicsofporcinecircovirustype2indifferentherdsfromintensivefarmsinchina2022 AT zhengyan infectioncharacteristicsofporcinecircovirustype2indifferentherdsfromintensivefarmsinchina2022 AT jingren infectioncharacteristicsofporcinecircovirustype2indifferentherdsfromintensivefarmsinchina2022 AT xiaowenli infectioncharacteristicsofporcinecircovirustype2indifferentherdsfromintensivefarmsinchina2022 AT xiaowenli infectioncharacteristicsofporcinecircovirustype2indifferentherdsfromintensivefarmsinchina2022 AT xiaowenli infectioncharacteristicsofporcinecircovirustype2indifferentherdsfromintensivefarmsinchina2022 AT xiaowenli infectioncharacteristicsofporcinecircovirustype2indifferentherdsfromintensivefarmsinchina2022 |