Overview of Metabolomic Analysis and the Integration with Multi-Omics for Economic Traits in Cattle
Metabolomics has been applied to measure the dynamic metabolic responses, to understand the systematic biological networks, to reveal the potential genetic architecture, etc., for human diseases and livestock traits. For example, the current published results include the detected relevant candidate...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-10-01
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| Series: | Metabolites |
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| Online Access: | https://www.mdpi.com/2218-1989/11/11/753 |
| _version_ | 1797509345134510080 |
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| author | Dan Hao Jiangsong Bai Jianyong Du Xiaoping Wu Bo Thomsen Hongding Gao Guosheng Su Xiao Wang |
| author_facet | Dan Hao Jiangsong Bai Jianyong Du Xiaoping Wu Bo Thomsen Hongding Gao Guosheng Su Xiao Wang |
| author_sort | Dan Hao |
| collection | DOAJ |
| description | Metabolomics has been applied to measure the dynamic metabolic responses, to understand the systematic biological networks, to reveal the potential genetic architecture, etc., for human diseases and livestock traits. For example, the current published results include the detected relevant candidate metabolites, identified metabolic pathways, potential systematic networks, etc., for different cattle traits that can be applied for further metabolomic and integrated omics studies. Therefore, summarizing the applications of metabolomics for economic traits is required in cattle. We here provide a comprehensive review about metabolomic analysis and its integration with other omics in five aspects: (1) characterization of the metabolomic profile of cattle; (2) metabolomic applications in cattle; (3) integrated metabolomic analysis with other omics; (4) methods and tools in metabolomic analysis; and (5) further potentialities. The review aims to investigate the existing metabolomic studies by highlighting the results in cattle, integrated with other omics studies, to understand the metabolic mechanisms underlying the economic traits and to provide useful information for further research and practical breeding programs in cattle. |
| first_indexed | 2024-03-10T05:16:25Z |
| format | Article |
| id | doaj.art-0f84621cf3ba4477a18deab78e63a300 |
| institution | Directory Open Access Journal |
| issn | 2218-1989 |
| language | English |
| last_indexed | 2024-03-10T05:16:25Z |
| publishDate | 2021-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Metabolites |
| spelling | doaj.art-0f84621cf3ba4477a18deab78e63a3002023-11-23T00:21:02ZengMDPI AGMetabolites2218-19892021-10-01111175310.3390/metabo11110753Overview of Metabolomic Analysis and the Integration with Multi-Omics for Economic Traits in CattleDan Hao0Jiangsong Bai1Jianyong Du2Xiaoping Wu3Bo Thomsen4Hongding Gao5Guosheng Su6Xiao Wang7Beijing Zhongnongtongchuang (ZNTC) Biotechnology Co., Ltd., Beijing 100193, ChinaBeijing Zhongnongtongchuang (ZNTC) Biotechnology Co., Ltd., Beijing 100193, ChinaBeijing Zhongnongtongchuang (ZNTC) Biotechnology Co., Ltd., Beijing 100193, ChinaBeijing Zhongnongtongchuang (ZNTC) Biotechnology Co., Ltd., Beijing 100193, ChinaDepartment of Molecular Biology and Genetics, Aarhus University, 8000 Aarhus, DenmarkCenter for Quantitative Genetics and Genomics, Aarhus University, 8830 Tjele, DenmarkCenter for Quantitative Genetics and Genomics, Aarhus University, 8830 Tjele, DenmarkKonge Larsen ApS, 2800 Kongens Lyngby, DenmarkMetabolomics has been applied to measure the dynamic metabolic responses, to understand the systematic biological networks, to reveal the potential genetic architecture, etc., for human diseases and livestock traits. For example, the current published results include the detected relevant candidate metabolites, identified metabolic pathways, potential systematic networks, etc., for different cattle traits that can be applied for further metabolomic and integrated omics studies. Therefore, summarizing the applications of metabolomics for economic traits is required in cattle. We here provide a comprehensive review about metabolomic analysis and its integration with other omics in five aspects: (1) characterization of the metabolomic profile of cattle; (2) metabolomic applications in cattle; (3) integrated metabolomic analysis with other omics; (4) methods and tools in metabolomic analysis; and (5) further potentialities. The review aims to investigate the existing metabolomic studies by highlighting the results in cattle, integrated with other omics studies, to understand the metabolic mechanisms underlying the economic traits and to provide useful information for further research and practical breeding programs in cattle.https://www.mdpi.com/2218-1989/11/11/753cattlemetabolomicsmulti-omicsintegrated analysiseconomic traitreview |
| spellingShingle | Dan Hao Jiangsong Bai Jianyong Du Xiaoping Wu Bo Thomsen Hongding Gao Guosheng Su Xiao Wang Overview of Metabolomic Analysis and the Integration with Multi-Omics for Economic Traits in Cattle Metabolites cattle metabolomics multi-omics integrated analysis economic trait review |
| title | Overview of Metabolomic Analysis and the Integration with Multi-Omics for Economic Traits in Cattle |
| title_full | Overview of Metabolomic Analysis and the Integration with Multi-Omics for Economic Traits in Cattle |
| title_fullStr | Overview of Metabolomic Analysis and the Integration with Multi-Omics for Economic Traits in Cattle |
| title_full_unstemmed | Overview of Metabolomic Analysis and the Integration with Multi-Omics for Economic Traits in Cattle |
| title_short | Overview of Metabolomic Analysis and the Integration with Multi-Omics for Economic Traits in Cattle |
| title_sort | overview of metabolomic analysis and the integration with multi omics for economic traits in cattle |
| topic | cattle metabolomics multi-omics integrated analysis economic trait review |
| url | https://www.mdpi.com/2218-1989/11/11/753 |
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