Obesity and Hyperglycemia in Korean Men with Klinefelter Syndrome: The Korean Endocrine Society Registry

BackgroundThe aim of this study was to investigate the prevalence of obesity in Korean men with Klinefelter syndrome (KS) and the associated risk factors for obesity and hyperglycemia.MethodsData were collected retrospectively from medical records from 11 university hospitals in Korea between 1994 a...

Full description

Bibliographic Details
Main Authors: Seung Jin Han, Kyung-Soo Kim, Wonjin Kim, Jung Hee Kim, Yong-ho Lee, Ji Sun Nam, Ji A Seo, Bu Kyung Kim, Jihyun Lee, Jin Ook Chung, Min-Hee Kim, Tae-Seo Sohn, Han Seok Choi, Seong Bin Hong, Yoon-Sok Chung
Format: Article
Language:English
Published: Korean Endocrine Society 2016-12-01
Series:Endocrinology and Metabolism
Subjects:
Online Access:http://e-enm.org/Synapse/Data/PDFData/2008ENM/enm-31-598.pdf
_version_ 1818568438081126400
author Seung Jin Han
Kyung-Soo Kim
Wonjin Kim
Jung Hee Kim
Yong-ho Lee
Ji Sun Nam
Ji A Seo
Bu Kyung Kim
Jihyun Lee
Jin Ook Chung
Min-Hee Kim
Tae-Seo Sohn
Han Seok Choi
Seong Bin Hong
Yoon-Sok Chung
author_facet Seung Jin Han
Kyung-Soo Kim
Wonjin Kim
Jung Hee Kim
Yong-ho Lee
Ji Sun Nam
Ji A Seo
Bu Kyung Kim
Jihyun Lee
Jin Ook Chung
Min-Hee Kim
Tae-Seo Sohn
Han Seok Choi
Seong Bin Hong
Yoon-Sok Chung
author_sort Seung Jin Han
collection DOAJ
description BackgroundThe aim of this study was to investigate the prevalence of obesity in Korean men with Klinefelter syndrome (KS) and the associated risk factors for obesity and hyperglycemia.MethodsData were collected retrospectively from medical records from 11 university hospitals in Korea between 1994 and 2014. Subjects aged ≥18 years with newly diagnosed KS were enrolled. The following parameters were recorded at baseline before treatment: chief complaint, height, weight, fasting glucose level, lipid panel, blood pressure, testosterone, luteinizing hormone, follicle-stimulating hormone, karyotyping patterns, and history of hypertension, diabetes, and dyslipidemia.ResultsData were analyzed from 376 of 544 initially enrolled patients. The rate of the 47 XXY chromosomal pattern was 94.1%. The prevalence of obesity (body mass index ≥25 kg/m2) in Korean men with KS was 42.6%. The testosterone level was an independent risk factor for obesity and hyperglycemia.ConclusionObesity is common in Korean men with KS. Hypogonadism in patients with KS was associated with obesity and hyperglycemia.
first_indexed 2024-12-14T06:35:29Z
format Article
id doaj.art-0f89838f51334e0e982da8be2b1999d3
institution Directory Open Access Journal
issn 2093-596X
2093-5978
language English
last_indexed 2024-12-14T06:35:29Z
publishDate 2016-12-01
publisher Korean Endocrine Society
record_format Article
series Endocrinology and Metabolism
spelling doaj.art-0f89838f51334e0e982da8be2b1999d32022-12-21T23:13:22ZengKorean Endocrine SocietyEndocrinology and Metabolism2093-596X2093-59782016-12-0131459860310.3803/EnM.2016.31.4.59821723Obesity and Hyperglycemia in Korean Men with Klinefelter Syndrome: The Korean Endocrine Society RegistrySeung Jin HanKyung-Soo KimWonjin KimJung Hee KimYong-ho LeeJi Sun NamJi A SeoBu Kyung KimJihyun LeeJin Ook ChungMin-Hee KimTae-Seo SohnHan Seok ChoiSeong Bin HongYoon-Sok ChungBackgroundThe aim of this study was to investigate the prevalence of obesity in Korean men with Klinefelter syndrome (KS) and the associated risk factors for obesity and hyperglycemia.MethodsData were collected retrospectively from medical records from 11 university hospitals in Korea between 1994 and 2014. Subjects aged ≥18 years with newly diagnosed KS were enrolled. The following parameters were recorded at baseline before treatment: chief complaint, height, weight, fasting glucose level, lipid panel, blood pressure, testosterone, luteinizing hormone, follicle-stimulating hormone, karyotyping patterns, and history of hypertension, diabetes, and dyslipidemia.ResultsData were analyzed from 376 of 544 initially enrolled patients. The rate of the 47 XXY chromosomal pattern was 94.1%. The prevalence of obesity (body mass index ≥25 kg/m2) in Korean men with KS was 42.6%. The testosterone level was an independent risk factor for obesity and hyperglycemia.ConclusionObesity is common in Korean men with KS. Hypogonadism in patients with KS was associated with obesity and hyperglycemia.http://e-enm.org/Synapse/Data/PDFData/2008ENM/enm-31-598.pdfKlinefelter syndromeObesityHyperglycemia
spellingShingle Seung Jin Han
Kyung-Soo Kim
Wonjin Kim
Jung Hee Kim
Yong-ho Lee
Ji Sun Nam
Ji A Seo
Bu Kyung Kim
Jihyun Lee
Jin Ook Chung
Min-Hee Kim
Tae-Seo Sohn
Han Seok Choi
Seong Bin Hong
Yoon-Sok Chung
Obesity and Hyperglycemia in Korean Men with Klinefelter Syndrome: The Korean Endocrine Society Registry
Endocrinology and Metabolism
Klinefelter syndrome
Obesity
Hyperglycemia
title Obesity and Hyperglycemia in Korean Men with Klinefelter Syndrome: The Korean Endocrine Society Registry
title_full Obesity and Hyperglycemia in Korean Men with Klinefelter Syndrome: The Korean Endocrine Society Registry
title_fullStr Obesity and Hyperglycemia in Korean Men with Klinefelter Syndrome: The Korean Endocrine Society Registry
title_full_unstemmed Obesity and Hyperglycemia in Korean Men with Klinefelter Syndrome: The Korean Endocrine Society Registry
title_short Obesity and Hyperglycemia in Korean Men with Klinefelter Syndrome: The Korean Endocrine Society Registry
title_sort obesity and hyperglycemia in korean men with klinefelter syndrome the korean endocrine society registry
topic Klinefelter syndrome
Obesity
Hyperglycemia
url http://e-enm.org/Synapse/Data/PDFData/2008ENM/enm-31-598.pdf
work_keys_str_mv AT seungjinhan obesityandhyperglycemiainkoreanmenwithklinefeltersyndromethekoreanendocrinesocietyregistry
AT kyungsookim obesityandhyperglycemiainkoreanmenwithklinefeltersyndromethekoreanendocrinesocietyregistry
AT wonjinkim obesityandhyperglycemiainkoreanmenwithklinefeltersyndromethekoreanendocrinesocietyregistry
AT jungheekim obesityandhyperglycemiainkoreanmenwithklinefeltersyndromethekoreanendocrinesocietyregistry
AT yongholee obesityandhyperglycemiainkoreanmenwithklinefeltersyndromethekoreanendocrinesocietyregistry
AT jisunnam obesityandhyperglycemiainkoreanmenwithklinefeltersyndromethekoreanendocrinesocietyregistry
AT jiaseo obesityandhyperglycemiainkoreanmenwithklinefeltersyndromethekoreanendocrinesocietyregistry
AT bukyungkim obesityandhyperglycemiainkoreanmenwithklinefeltersyndromethekoreanendocrinesocietyregistry
AT jihyunlee obesityandhyperglycemiainkoreanmenwithklinefeltersyndromethekoreanendocrinesocietyregistry
AT jinookchung obesityandhyperglycemiainkoreanmenwithklinefeltersyndromethekoreanendocrinesocietyregistry
AT minheekim obesityandhyperglycemiainkoreanmenwithklinefeltersyndromethekoreanendocrinesocietyregistry
AT taeseosohn obesityandhyperglycemiainkoreanmenwithklinefeltersyndromethekoreanendocrinesocietyregistry
AT hanseokchoi obesityandhyperglycemiainkoreanmenwithklinefeltersyndromethekoreanendocrinesocietyregistry
AT seongbinhong obesityandhyperglycemiainkoreanmenwithklinefeltersyndromethekoreanendocrinesocietyregistry
AT yoonsokchung obesityandhyperglycemiainkoreanmenwithklinefeltersyndromethekoreanendocrinesocietyregistry