Comparative phylogenomics uncovers the impact of symbiotic associations on host genome evolution.
Mutualistic symbioses between eukaryotes and beneficial microorganisms of their microbiome play an essential role in nutrition, protection against disease, and development of the host. However, the impact of beneficial symbionts on the evolution of host genomes remains poorly characterized. Here we...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2014-07-01
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| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC4102449?pdf=render |
| _version_ | 1818552293195251712 |
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| author | Pierre-Marc Delaux Kranthi Varala Patrick P Edger Gloria M Coruzzi J Chris Pires Jean-Michel Ané |
| author_facet | Pierre-Marc Delaux Kranthi Varala Patrick P Edger Gloria M Coruzzi J Chris Pires Jean-Michel Ané |
| author_sort | Pierre-Marc Delaux |
| collection | DOAJ |
| description | Mutualistic symbioses between eukaryotes and beneficial microorganisms of their microbiome play an essential role in nutrition, protection against disease, and development of the host. However, the impact of beneficial symbionts on the evolution of host genomes remains poorly characterized. Here we used the independent loss of the most widespread plant-microbe symbiosis, arbuscular mycorrhization (AM), as a model to address this question. Using a large phenotypic approach and phylogenetic analyses, we present evidence that loss of AM symbiosis correlates with the loss of many symbiotic genes in the Arabidopsis lineage (Brassicales). Then, by analyzing the genome and/or transcriptomes of nine other phylogenetically divergent non-host plants, we show that this correlation occurred in a convergent manner in four additional plant lineages, demonstrating the existence of an evolutionary pattern specific to symbiotic genes. Finally, we use a global comparative phylogenomic approach to track this evolutionary pattern among land plants. Based on this approach, we identify a set of 174 highly conserved genes and demonstrate enrichment in symbiosis-related genes. Our findings are consistent with the hypothesis that beneficial symbionts maintain purifying selection on host gene networks during the evolution of entire lineages. |
| first_indexed | 2024-12-12T09:11:18Z |
| format | Article |
| id | doaj.art-0f90befd84b24078801208fc7fa073cb |
| institution | Directory Open Access Journal |
| issn | 1553-7390 1553-7404 |
| language | English |
| last_indexed | 2024-12-12T09:11:18Z |
| publishDate | 2014-07-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS Genetics |
| spelling | doaj.art-0f90befd84b24078801208fc7fa073cb2022-12-22T00:29:30ZengPublic Library of Science (PLoS)PLoS Genetics1553-73901553-74042014-07-01107e100448710.1371/journal.pgen.1004487Comparative phylogenomics uncovers the impact of symbiotic associations on host genome evolution.Pierre-Marc DelauxKranthi VaralaPatrick P EdgerGloria M CoruzziJ Chris PiresJean-Michel AnéMutualistic symbioses between eukaryotes and beneficial microorganisms of their microbiome play an essential role in nutrition, protection against disease, and development of the host. However, the impact of beneficial symbionts on the evolution of host genomes remains poorly characterized. Here we used the independent loss of the most widespread plant-microbe symbiosis, arbuscular mycorrhization (AM), as a model to address this question. Using a large phenotypic approach and phylogenetic analyses, we present evidence that loss of AM symbiosis correlates with the loss of many symbiotic genes in the Arabidopsis lineage (Brassicales). Then, by analyzing the genome and/or transcriptomes of nine other phylogenetically divergent non-host plants, we show that this correlation occurred in a convergent manner in four additional plant lineages, demonstrating the existence of an evolutionary pattern specific to symbiotic genes. Finally, we use a global comparative phylogenomic approach to track this evolutionary pattern among land plants. Based on this approach, we identify a set of 174 highly conserved genes and demonstrate enrichment in symbiosis-related genes. Our findings are consistent with the hypothesis that beneficial symbionts maintain purifying selection on host gene networks during the evolution of entire lineages.http://europepmc.org/articles/PMC4102449?pdf=render |
| spellingShingle | Pierre-Marc Delaux Kranthi Varala Patrick P Edger Gloria M Coruzzi J Chris Pires Jean-Michel Ané Comparative phylogenomics uncovers the impact of symbiotic associations on host genome evolution. PLoS Genetics |
| title | Comparative phylogenomics uncovers the impact of symbiotic associations on host genome evolution. |
| title_full | Comparative phylogenomics uncovers the impact of symbiotic associations on host genome evolution. |
| title_fullStr | Comparative phylogenomics uncovers the impact of symbiotic associations on host genome evolution. |
| title_full_unstemmed | Comparative phylogenomics uncovers the impact of symbiotic associations on host genome evolution. |
| title_short | Comparative phylogenomics uncovers the impact of symbiotic associations on host genome evolution. |
| title_sort | comparative phylogenomics uncovers the impact of symbiotic associations on host genome evolution |
| url | http://europepmc.org/articles/PMC4102449?pdf=render |
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