A multi-center analysis of single-fraction versus hypofractionated stereotactic radiosurgery for the treatment of brain metastasis

A multi-center analysis of single-fraction versus hypofractionated stereotactic radiosurgery for the treatment of brain metastasis

Abstract Background Hypofractionated-SRS (HF-SRS) may allow for improved local control and a reduced risk of radiation necrosis compared to single-fraction-SRS (SF-SRS). However, data comparing these two treatment approaches are limited. The purpose of this study was to compare clinical outcomes bet...

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Bibliographic Details
Main Authors: Jill S. Remick, Emily Kowalski, Rahul Khairnar, Kai Sun, Emily Morse, Hua-Ren R. Cherng, Yannick Poirier, Narottam Lamichhane, Stewart J. Becker, Shifeng Chen, Akshar N. Patel, Young Kwok, Elizabeth Nichols, Pranshu Mohindra, Graeme F. Woodworth, William F. Regine, Mark V. Mishra
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Radiation Oncology
Subjects:
Brain metastasis
Stereotactic radiosurgery
Hypofractionated stereotactic radiosurgery
GammaKnife
Normal tissue injury
Biologic effective dose
Online Access:http://link.springer.com/article/10.1186/s13014-020-01522-6

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