Correlation of Dermatoglyphics with Clinical Characteristics of Cervix Carcinoma Patients at a Tertiary Care Centre in Kanpur, Uttar Pradesh, India
Introduction: Cervix cancer is most prevalent cancer in females. Early detection and regular screening methods are helpful for the prevention of cervix cancer related morbidity and mortality. Early stages of development, dermatoglyphic features are generated under genetic influences, but they can be...
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| Format: | Article |
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JCDR Research and Publications Private Limited
2022-03-01
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| Series: | Journal of Clinical and Diagnostic Research |
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| Online Access: | https://www.jcdr.net/articles/PDF/16092/52963_CE[Ra1]_F(KR)_PF1(AG_SS)_PFA(SL)_PB(AG_SL)_PN(KM).pdf |
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| author | K Pravallika Vandana Tewari Sheela Sharma Anil Kumar |
| author_facet | K Pravallika Vandana Tewari Sheela Sharma Anil Kumar |
| author_sort | K Pravallika |
| collection | DOAJ |
| description | Introduction: Cervix cancer is most prevalent cancer in females. Early detection and regular screening methods are helpful for the prevention of cervix cancer related morbidity and mortality. Early stages of development, dermatoglyphic features are generated under genetic influences, but they can be influenced by environmental variables during the first three months of pregnancy. These trends may reflect an individual’s genetic make-up and, as a result, his or her proclivity for particular diseases. Therefore, the dermatoglyphic prints may serves as a non invasive anatomic marker of cervix cancer risk, allowing for early detection and treatment.
Aim: To characterise dermatoglyphics in cervix cancer patients and correlate them to principal clinical features.
Materials and Methods: This cross-sectional study included 300 cervix cancer patients, analysed the clinical presentations and dermatoglyphics prospectively after obtaining ethics approval from a tertiary care hospital, Kanpur, Uttar Pradesh, India, during December 2016 to January 2020. The palmar dermatoglyphics (loops, arches, whorls and palmar angle) were obtained and evaluated for correlation with principal clinical features like vaginal discharge, postmenopausal bleeding, and intermenstrual bleeding using Spearman’s correlation test.
Results: In this study, the frequencies of arches, loops and whorls were 81, 2051, 868 respectively. A strong positive correlation (r>0.92) existed between whorls of palmar digits and clinical features of cervix cancer.
Conclusion: Dermatoglyphic patterns could be used to investigate the genetic cause of cervix cancer and could potentially be used as a non invasive anatomical screening method in high-risk patients. |
| first_indexed | 2024-04-10T20:33:33Z |
| format | Article |
| id | doaj.art-0f95166212914dd98c0a53629c883b93 |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-04-10T20:33:33Z |
| publishDate | 2022-03-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-0f95166212914dd98c0a53629c883b932023-01-25T04:17:00ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2022-03-01163AC01AC0410.7860/JCDR/2022/52963.16092Correlation of Dermatoglyphics with Clinical Characteristics of Cervix Carcinoma Patients at a Tertiary Care Centre in Kanpur, Uttar Pradesh, IndiaK Pravallika 0Vandana Tewari1Sheela Sharma2Anil Kumar3Research Scholar, Department of Anatomy, Rama Medical College Hospital and Research Centre, Kanpur, Uttar Pradesh, India.Professor, Department of Anatomy, Rama Medical College Hospital and Research Centre, Kanpur, Uttar Pradesh, India.Professor and Head, Department of Obstetrics and Gynaecology, Rama Medical College Hospital and Research Centre, Kanpur, Uttar Pradesh, India.Assistant Professor, Department of Central Research Laboratory, Rama Medical College Hospital and Research Centre, Kanpur, Uttar Pradesh, India.Introduction: Cervix cancer is most prevalent cancer in females. Early detection and regular screening methods are helpful for the prevention of cervix cancer related morbidity and mortality. Early stages of development, dermatoglyphic features are generated under genetic influences, but they can be influenced by environmental variables during the first three months of pregnancy. These trends may reflect an individual’s genetic make-up and, as a result, his or her proclivity for particular diseases. Therefore, the dermatoglyphic prints may serves as a non invasive anatomic marker of cervix cancer risk, allowing for early detection and treatment. Aim: To characterise dermatoglyphics in cervix cancer patients and correlate them to principal clinical features. Materials and Methods: This cross-sectional study included 300 cervix cancer patients, analysed the clinical presentations and dermatoglyphics prospectively after obtaining ethics approval from a tertiary care hospital, Kanpur, Uttar Pradesh, India, during December 2016 to January 2020. The palmar dermatoglyphics (loops, arches, whorls and palmar angle) were obtained and evaluated for correlation with principal clinical features like vaginal discharge, postmenopausal bleeding, and intermenstrual bleeding using Spearman’s correlation test. Results: In this study, the frequencies of arches, loops and whorls were 81, 2051, 868 respectively. A strong positive correlation (r>0.92) existed between whorls of palmar digits and clinical features of cervix cancer. Conclusion: Dermatoglyphic patterns could be used to investigate the genetic cause of cervix cancer and could potentially be used as a non invasive anatomical screening method in high-risk patients.https://www.jcdr.net/articles/PDF/16092/52963_CE[Ra1]_F(KR)_PF1(AG_SS)_PFA(SL)_PB(AG_SL)_PN(KM).pdfanatomical toolclinical featurespalmar ridgestriradiiuterine-cervix cancer |
| spellingShingle | K Pravallika Vandana Tewari Sheela Sharma Anil Kumar Correlation of Dermatoglyphics with Clinical Characteristics of Cervix Carcinoma Patients at a Tertiary Care Centre in Kanpur, Uttar Pradesh, India Journal of Clinical and Diagnostic Research anatomical tool clinical features palmar ridges triradii uterine-cervix cancer |
| title | Correlation of Dermatoglyphics with Clinical Characteristics of Cervix Carcinoma Patients at a Tertiary Care Centre in Kanpur, Uttar Pradesh, India |
| title_full | Correlation of Dermatoglyphics with Clinical Characteristics of Cervix Carcinoma Patients at a Tertiary Care Centre in Kanpur, Uttar Pradesh, India |
| title_fullStr | Correlation of Dermatoglyphics with Clinical Characteristics of Cervix Carcinoma Patients at a Tertiary Care Centre in Kanpur, Uttar Pradesh, India |
| title_full_unstemmed | Correlation of Dermatoglyphics with Clinical Characteristics of Cervix Carcinoma Patients at a Tertiary Care Centre in Kanpur, Uttar Pradesh, India |
| title_short | Correlation of Dermatoglyphics with Clinical Characteristics of Cervix Carcinoma Patients at a Tertiary Care Centre in Kanpur, Uttar Pradesh, India |
| title_sort | correlation of dermatoglyphics with clinical characteristics of cervix carcinoma patients at a tertiary care centre in kanpur uttar pradesh india |
| topic | anatomical tool clinical features palmar ridges triradii uterine-cervix cancer |
| url | https://www.jcdr.net/articles/PDF/16092/52963_CE[Ra1]_F(KR)_PF1(AG_SS)_PFA(SL)_PB(AG_SL)_PN(KM).pdf |
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