Likely role of APOBEC3G-mediated G-to-A mutations in HIV-1 evolution and drug resistance.
The role of APOBEC3 (A3) protein family members in inhibiting retrovirus infection and mobile element retrotransposition is well established. However, the evolutionary effects these restriction factors may have had on active retroviruses such as HIV-1 are less well understood. An HIV-1 variant that...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2009-04-01
|
| Series: | PLoS Pathogens |
| Online Access: | http://europepmc.org/articles/PMC2659435?pdf=render |