Impact of bowel space contouring variability on radiation dose and volume assessments in treatment planning for gynaecologic cancers
Abstract Introduction Correlations between radiation dose/volume measures and small bowel (SB) toxicity are inconsistent in the medical literature. We assessed the impact of inter‐provider variation in bowel bag contouring technique on estimates of radiation dose received by the SB during pelvic rad...
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| Format: | Article |
| Language: | English |
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Wiley
2023-12-01
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| Series: | Journal of Medical Radiation Sciences |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/jmrs.703 |
| _version_ | 1827586449668571136 |
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| author | Fatjona Kraja Kevin Kauweloa Rohit G. Ganju Andrew C. Hoover |
| author_facet | Fatjona Kraja Kevin Kauweloa Rohit G. Ganju Andrew C. Hoover |
| author_sort | Fatjona Kraja |
| collection | DOAJ |
| description | Abstract Introduction Correlations between radiation dose/volume measures and small bowel (SB) toxicity are inconsistent in the medical literature. We assessed the impact of inter‐provider variation in bowel bag contouring technique on estimates of radiation dose received by the SB during pelvic radiotherapy. Methods Ten radiation oncologists contoured rectum, bladder and bowel bags on treatment planning computed tomography (CT) scans of two patients receiving adjuvant radiation for endometrial cancer. A radiation plan was generated for each patient and used to determine the radiation dose/volume for each organ. Kappa statistics were applied to assess the inter‐provider contouring agreement, and Levene test evaluated the homogeneity of variance for radiation dose/volume metrics, including the V45Gy (cm3). Results The bowel bag showed greater variation in radiation dose/volume estimates compared to the bladder and rectum. The V45Gy ranged from 163 to 384 cm3 for data set A and 109 to 409 cm3 for dataset B. Kappa values were 0.82/0.83, 0.92/0.92 and 0.94/0.86 for the bowel bag, rectum, and bladder on data sets A/B, demonstrating lower inter‐provider agreement for bowel bag compared with bladder and rectum. Conclusion Inter‐provider contouring variability is more significant for the bowel bag than the rectum and bladder, with an associated greater variability in dose and volume estimates during radiation planning. |
| first_indexed | 2024-03-09T00:02:39Z |
| format | Article |
| id | doaj.art-0f962516f760449bb4daf668e7c587b1 |
| institution | Directory Open Access Journal |
| issn | 2051-3895 2051-3909 |
| language | English |
| last_indexed | 2024-03-09T00:02:39Z |
| publishDate | 2023-12-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Medical Radiation Sciences |
| spelling | doaj.art-0f962516f760449bb4daf668e7c587b12023-12-12T15:36:38ZengWileyJournal of Medical Radiation Sciences2051-38952051-39092023-12-0170441742310.1002/jmrs.703Impact of bowel space contouring variability on radiation dose and volume assessments in treatment planning for gynaecologic cancersFatjona Kraja0Kevin Kauweloa1Rohit G. Ganju2Andrew C. Hoover3Department of Oncology University Hospital Centre Mother Teresa Tirana AlbaniaDepartment of Radiation Oncology Queen's Medical Centre Honolulu Hawaii USAWellstar Medical Group Alpharetta Georgia USADepartment of Radiation Oncology University of Kansas Cancer Centre, Kansas University Medical Centre Kansas City Kansas USAAbstract Introduction Correlations between radiation dose/volume measures and small bowel (SB) toxicity are inconsistent in the medical literature. We assessed the impact of inter‐provider variation in bowel bag contouring technique on estimates of radiation dose received by the SB during pelvic radiotherapy. Methods Ten radiation oncologists contoured rectum, bladder and bowel bags on treatment planning computed tomography (CT) scans of two patients receiving adjuvant radiation for endometrial cancer. A radiation plan was generated for each patient and used to determine the radiation dose/volume for each organ. Kappa statistics were applied to assess the inter‐provider contouring agreement, and Levene test evaluated the homogeneity of variance for radiation dose/volume metrics, including the V45Gy (cm3). Results The bowel bag showed greater variation in radiation dose/volume estimates compared to the bladder and rectum. The V45Gy ranged from 163 to 384 cm3 for data set A and 109 to 409 cm3 for dataset B. Kappa values were 0.82/0.83, 0.92/0.92 and 0.94/0.86 for the bowel bag, rectum, and bladder on data sets A/B, demonstrating lower inter‐provider agreement for bowel bag compared with bladder and rectum. Conclusion Inter‐provider contouring variability is more significant for the bowel bag than the rectum and bladder, with an associated greater variability in dose and volume estimates during radiation planning.https://doi.org/10.1002/jmrs.703Pelvisradiation oncologytechnique |
| spellingShingle | Fatjona Kraja Kevin Kauweloa Rohit G. Ganju Andrew C. Hoover Impact of bowel space contouring variability on radiation dose and volume assessments in treatment planning for gynaecologic cancers Journal of Medical Radiation Sciences Pelvis radiation oncology technique |
| title | Impact of bowel space contouring variability on radiation dose and volume assessments in treatment planning for gynaecologic cancers |
| title_full | Impact of bowel space contouring variability on radiation dose and volume assessments in treatment planning for gynaecologic cancers |
| title_fullStr | Impact of bowel space contouring variability on radiation dose and volume assessments in treatment planning for gynaecologic cancers |
| title_full_unstemmed | Impact of bowel space contouring variability on radiation dose and volume assessments in treatment planning for gynaecologic cancers |
| title_short | Impact of bowel space contouring variability on radiation dose and volume assessments in treatment planning for gynaecologic cancers |
| title_sort | impact of bowel space contouring variability on radiation dose and volume assessments in treatment planning for gynaecologic cancers |
| topic | Pelvis radiation oncology technique |
| url | https://doi.org/10.1002/jmrs.703 |
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