Role of Inflammatory Factors in Mediating the Effect of Lipids on Nonalcoholic Fatty Liver Disease: A Two-Step, Multivariable Mendelian Randomization Study

Role of Inflammatory Factors in Mediating the Effect of Lipids on Nonalcoholic Fatty Liver Disease: A Two-Step, Multivariable Mendelian Randomization Study

Aims/hypothesis: 20–80% of Nonalcoholic Fatty Liver Disease (NAFLD) have been observed to have dyslipidemia. Nevertheless, the probable mechanism of dyslipidemia’s effect on NAFLD remains unclear. Mendelian randomization (MR) was utilized to investigate the relationship between lipids, inflammatory...

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Bibliographic Details
Main Authors: Junhong Chen, Hao Zhou, Hengwei Jin, Kai Liu
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Nutrients
Subjects:
inflammatory factors
lipids
nonalcoholic fatty liver disease
Mendelian randomization
mediation
Online Access:https://www.mdpi.com/2072-6643/14/20/4434

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