Factors Determining Primary Coronary Slow Flow Phenomenon among Opium Users and Non-users: A Case Control Study in Northern Iran
Background: Coronary slow flow phenomenon (CSFP) represents a clinical entity with recurrent chest pain leading to living impairment. The present study aimed to investigate whether opium use correlates with primary CSFP. Methods: This study included Iranian patients with suspected coronary artery di...
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| Format: | Article |
| Language: | English |
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Kerman University of Medical Sciences
2022-07-01
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| Series: | Addiction and Health |
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| Online Access: | https://ahj.kmu.ac.ir/article_92058_e14e65ff96420222801d877038b746f8.pdf |
| _version_ | 1797693666370781184 |
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| author | Hamid Reza Javadi Seyed Mostafa Mirakbari Abbas Allami Ebrahim Salavati |
| author_facet | Hamid Reza Javadi Seyed Mostafa Mirakbari Abbas Allami Ebrahim Salavati |
| author_sort | Hamid Reza Javadi |
| collection | DOAJ |
| description | Background: Coronary slow flow phenomenon (CSFP) represents a clinical entity with recurrent chest pain leading to living impairment. The present study aimed to investigate whether opium use correlates with primary CSFP.
Methods: This study included Iranian patients with suspected coronary artery disease who underwent myocardial perfusion imaging. Coronary blood flow was measured quantitatively using the thrombolysis in myocardial infarction (TIMI) frame count and slow flow was defined as TIMI grade 2 standard deviations. Age and clinical conditions including diabetes mellitus (DM), hypertension (HTN), hyperlipidemia (HLP), history of chest pain, and opium use were recorded. First, the characteristics of the two groups were compared and then the main analyses were conducted to examine the relationship between CSFP and opium use. Data were analyzed using t test and chi-square test via SPSS 25.0. The significance level was set at P<0.05.
Findings: This study was conducted on 44 male patients with documented CSFP who had no stenotic lesions and 134 control group male patients who had normal coronary arteries with normal flow. The mean age was similar in the two groups (54.25 vs.52.69, P=0.474). Two groups were significantly different in terms of history of chest pain (P=0.003), but there was no significant difference in HTN (P=0.084), DM (P=0.284), HLP (P=0.183), smoking (P=0.696), and opium use (P=0.107).
Conclusion: This study indicated that opium use is not associated with primary CSFP. |
| first_indexed | 2024-03-12T02:46:53Z |
| format | Article |
| id | doaj.art-0f999907450540b3823ea64d1a04ee99 |
| institution | Directory Open Access Journal |
| issn | 2008-4633 2008-8469 |
| language | English |
| last_indexed | 2024-03-12T02:46:53Z |
| publishDate | 2022-07-01 |
| publisher | Kerman University of Medical Sciences |
| record_format | Article |
| series | Addiction and Health |
| spelling | doaj.art-0f999907450540b3823ea64d1a04ee992023-09-04T06:42:11ZengKerman University of Medical SciencesAddiction and Health2008-46332008-84692022-07-011432242810.34172/ahj.2022.121192058Factors Determining Primary Coronary Slow Flow Phenomenon among Opium Users and Non-users: A Case Control Study in Northern IranHamid Reza Javadi0Seyed Mostafa Mirakbari1Abbas Allami2Ebrahim Salavati3Department of Cardiology, Bu Ali Hospital, Qazvin University of Medical Sciences, Qazvin, IranDepartment of Clinical Toxicology, Bu Ali Hospital, Qazvin University of Medical Sciences, Qazvin, IranDepartment of Infectious Diseases, Bu Ali Hospital, Qazvin University of Medical Sciences, Qazvin, IranDepartment of Cardiology, Bu Ali Hospital, Qazvin University of Medical Sciences, Qazvin, IranBackground: Coronary slow flow phenomenon (CSFP) represents a clinical entity with recurrent chest pain leading to living impairment. The present study aimed to investigate whether opium use correlates with primary CSFP. Methods: This study included Iranian patients with suspected coronary artery disease who underwent myocardial perfusion imaging. Coronary blood flow was measured quantitatively using the thrombolysis in myocardial infarction (TIMI) frame count and slow flow was defined as TIMI grade 2 standard deviations. Age and clinical conditions including diabetes mellitus (DM), hypertension (HTN), hyperlipidemia (HLP), history of chest pain, and opium use were recorded. First, the characteristics of the two groups were compared and then the main analyses were conducted to examine the relationship between CSFP and opium use. Data were analyzed using t test and chi-square test via SPSS 25.0. The significance level was set at P<0.05. Findings: This study was conducted on 44 male patients with documented CSFP who had no stenotic lesions and 134 control group male patients who had normal coronary arteries with normal flow. The mean age was similar in the two groups (54.25 vs.52.69, P=0.474). Two groups were significantly different in terms of history of chest pain (P=0.003), but there was no significant difference in HTN (P=0.084), DM (P=0.284), HLP (P=0.183), smoking (P=0.696), and opium use (P=0.107). Conclusion: This study indicated that opium use is not associated with primary CSFP.https://ahj.kmu.ac.ir/article_92058_e14e65ff96420222801d877038b746f8.pdfangiographychest paincoronary artery diseaseopiumslow flow phenomenon |
| spellingShingle | Hamid Reza Javadi Seyed Mostafa Mirakbari Abbas Allami Ebrahim Salavati Factors Determining Primary Coronary Slow Flow Phenomenon among Opium Users and Non-users: A Case Control Study in Northern Iran Addiction and Health angiography chest pain coronary artery disease opium slow flow phenomenon |
| title | Factors Determining Primary Coronary Slow Flow Phenomenon among Opium Users and Non-users: A Case Control Study in Northern Iran |
| title_full | Factors Determining Primary Coronary Slow Flow Phenomenon among Opium Users and Non-users: A Case Control Study in Northern Iran |
| title_fullStr | Factors Determining Primary Coronary Slow Flow Phenomenon among Opium Users and Non-users: A Case Control Study in Northern Iran |
| title_full_unstemmed | Factors Determining Primary Coronary Slow Flow Phenomenon among Opium Users and Non-users: A Case Control Study in Northern Iran |
| title_short | Factors Determining Primary Coronary Slow Flow Phenomenon among Opium Users and Non-users: A Case Control Study in Northern Iran |
| title_sort | factors determining primary coronary slow flow phenomenon among opium users and non users a case control study in northern iran |
| topic | angiography chest pain coronary artery disease opium slow flow phenomenon |
| url | https://ahj.kmu.ac.ir/article_92058_e14e65ff96420222801d877038b746f8.pdf |
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