A novel wearable device for automated real-time detection of epileptic seizures
Abstract Background Epilepsy is a neurological disorder that has a variety of origins. It is caused by hyperexcitability and an imbalance between excitation and inhibition, which results in seizures. The World Health Organization (WHO) and its partners have classified epilepsy as a major public heal...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-07-01
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| Series: | BMC Biomedical Engineering |
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| Online Access: | https://doi.org/10.1186/s42490-023-00073-7 |
| _version_ | 1827895227707293696 |
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| author | Mikael Habtamu Keneni Tolosa Kidus Abera Lamesgin Demissie Samrawit Samuel Yeabsera Temesgen Elbetel Taye Zewde Ahmed Ali Dawud |
| author_facet | Mikael Habtamu Keneni Tolosa Kidus Abera Lamesgin Demissie Samrawit Samuel Yeabsera Temesgen Elbetel Taye Zewde Ahmed Ali Dawud |
| author_sort | Mikael Habtamu |
| collection | DOAJ |
| description | Abstract Background Epilepsy is a neurological disorder that has a variety of origins. It is caused by hyperexcitability and an imbalance between excitation and inhibition, which results in seizures. The World Health Organization (WHO) and its partners have classified epilepsy as a major public health concern. Over 50 million individuals globally are affected by epilepsy which shows that the patient’s family, social, educational, and vocational activities are severely limited if seizures are not controlled. Patients who suffer from epileptic seizures have emotional, behavioral, and neurological issues. Alerting systems using a wearable sensor are commonly used to detect epileptic seizures. However, most of the devices have no multimodal systems that increase sensitivity and lower the false discovery rate for screening and intervention of epileptic seizures. Therefore, the objective of this project was, to design and develop an efficient, economical, and automatically detecting epileptic seizure device in real-time. Methods Our design incorporates different sensors to assess the patient’s condition such as an accelerometer, pulsoxymeter and vibration sensor which process body movement, heart rate variability, oxygen denaturation, and jerky movement respectively. The algorithm for real-time detection of epileptic seizures is based on the following: acceleration increases to a higher value of 23.4 m/s2 or decreases to a lower value of 10 m/s2 as energy is absorbed by the body, the heart rate increases by 10 bpm from the normal heart rate, oxygen denaturation is below 90% and vibration should be out of the range of 3 Hz -17 Hz. Then, a pulsoxymeter device was used as a gold standard to compare the heart rate variability and oxygen saturation sensor readings. The accuracy of the accelerometer and vibration sensor was also tested by a fast-moving and vibrating normal person’s hand. Results The prototype was built and subjected to different tests and iterations. The proposed device was tested for accuracy, cost-effectiveness and ease of use. An acceptable accuracy was achieved for the accelerometer, pulsoxymeter, and vibration sensor measurements, and the prototype was built only with a component cost of less than 40 USD excluding design, manufacturing, and other costs. The design is tested to see if it fits the design criteria; the results of the tests reveal that a large portion of the scientific procedures utilized in this study to identify epileptic seizures is effective. Conclusion This project is objectively targeted to design a medical device with multimodal systems that enable us to accurately detect epileptic seizures by detecting symptoms commonly associated with an episode of epileptic seizure and notifying a caregiver for immediate assistance. The proposed device has a great impact on reducing epileptic seizer mortality, especially in low-resource settings where both expertise and treatment are scarce. |
| first_indexed | 2024-03-12T22:18:27Z |
| format | Article |
| id | doaj.art-0f9b605b966545938a98f4c5e007fd8a |
| institution | Directory Open Access Journal |
| issn | 2524-4426 |
| language | English |
| last_indexed | 2024-03-12T22:18:27Z |
| publishDate | 2023-07-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Biomedical Engineering |
| spelling | doaj.art-0f9b605b966545938a98f4c5e007fd8a2023-07-23T11:09:34ZengBMCBMC Biomedical Engineering2524-44262023-07-01511910.1186/s42490-023-00073-7A novel wearable device for automated real-time detection of epileptic seizuresMikael Habtamu0Keneni Tolosa1Kidus Abera2Lamesgin Demissie3Samrawit Samuel4Yeabsera Temesgen5Elbetel Taye Zewde6Ahmed Ali Dawud7School of Biomedical Engineering, Jimma Institute of Technology, Jimma UniversitySchool of Biomedical Engineering, Jimma Institute of Technology, Jimma UniversitySchool of Biomedical Engineering, Jimma Institute of Technology, Jimma UniversitySchool of Biomedical Engineering, Jimma Institute of Technology, Jimma UniversitySchool of Biomedical Engineering, Jimma Institute of Technology, Jimma UniversitySchool of Biomedical Engineering, Jimma Institute of Technology, Jimma UniversitySchool of Biomedical Engineering, Jimma Institute of Technology, Jimma UniversitySchool of Biomedical Engineering, Jimma Institute of Technology, Jimma UniversityAbstract Background Epilepsy is a neurological disorder that has a variety of origins. It is caused by hyperexcitability and an imbalance between excitation and inhibition, which results in seizures. The World Health Organization (WHO) and its partners have classified epilepsy as a major public health concern. Over 50 million individuals globally are affected by epilepsy which shows that the patient’s family, social, educational, and vocational activities are severely limited if seizures are not controlled. Patients who suffer from epileptic seizures have emotional, behavioral, and neurological issues. Alerting systems using a wearable sensor are commonly used to detect epileptic seizures. However, most of the devices have no multimodal systems that increase sensitivity and lower the false discovery rate for screening and intervention of epileptic seizures. Therefore, the objective of this project was, to design and develop an efficient, economical, and automatically detecting epileptic seizure device in real-time. Methods Our design incorporates different sensors to assess the patient’s condition such as an accelerometer, pulsoxymeter and vibration sensor which process body movement, heart rate variability, oxygen denaturation, and jerky movement respectively. The algorithm for real-time detection of epileptic seizures is based on the following: acceleration increases to a higher value of 23.4 m/s2 or decreases to a lower value of 10 m/s2 as energy is absorbed by the body, the heart rate increases by 10 bpm from the normal heart rate, oxygen denaturation is below 90% and vibration should be out of the range of 3 Hz -17 Hz. Then, a pulsoxymeter device was used as a gold standard to compare the heart rate variability and oxygen saturation sensor readings. The accuracy of the accelerometer and vibration sensor was also tested by a fast-moving and vibrating normal person’s hand. Results The prototype was built and subjected to different tests and iterations. The proposed device was tested for accuracy, cost-effectiveness and ease of use. An acceptable accuracy was achieved for the accelerometer, pulsoxymeter, and vibration sensor measurements, and the prototype was built only with a component cost of less than 40 USD excluding design, manufacturing, and other costs. The design is tested to see if it fits the design criteria; the results of the tests reveal that a large portion of the scientific procedures utilized in this study to identify epileptic seizures is effective. Conclusion This project is objectively targeted to design a medical device with multimodal systems that enable us to accurately detect epileptic seizures by detecting symptoms commonly associated with an episode of epileptic seizure and notifying a caregiver for immediate assistance. The proposed device has a great impact on reducing epileptic seizer mortality, especially in low-resource settings where both expertise and treatment are scarce.https://doi.org/10.1186/s42490-023-00073-7AccelerationEpileptic seizureJerky movementOxygen denaturationReal-time detectionWearable sensors |
| spellingShingle | Mikael Habtamu Keneni Tolosa Kidus Abera Lamesgin Demissie Samrawit Samuel Yeabsera Temesgen Elbetel Taye Zewde Ahmed Ali Dawud A novel wearable device for automated real-time detection of epileptic seizures BMC Biomedical Engineering Acceleration Epileptic seizure Jerky movement Oxygen denaturation Real-time detection Wearable sensors |
| title | A novel wearable device for automated real-time detection of epileptic seizures |
| title_full | A novel wearable device for automated real-time detection of epileptic seizures |
| title_fullStr | A novel wearable device for automated real-time detection of epileptic seizures |
| title_full_unstemmed | A novel wearable device for automated real-time detection of epileptic seizures |
| title_short | A novel wearable device for automated real-time detection of epileptic seizures |
| title_sort | novel wearable device for automated real time detection of epileptic seizures |
| topic | Acceleration Epileptic seizure Jerky movement Oxygen denaturation Real-time detection Wearable sensors |
| url | https://doi.org/10.1186/s42490-023-00073-7 |
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