Tumor suppressor PTEN regulation by tobacco smoke in lung squamous-cell carcinoma based on bioinformatics analysis

Tumor suppressor PTEN regulation by tobacco smoke in lung squamous-cell carcinoma based on bioinformatics analysis

Phosphatase and tensin homolog deleted on chromosome 10 (PTEN), is a tumor suppressor inactivated in a variety of human cancers. PTEN alteration correlates with lung squamous-cell carcinoma (LUSC) histology. However, it is still unclear how tobacco smoke regulates PTEN in LUSC tissues. In this study...

Full description

Bibliographic Details
Main Authors: Vladimir O. Pustylnyak, Efim Y. Alekseenok, Alina M. Perevalova, Vadim V. Kozlov, Lyudmila F. Gulyaeva
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:Heliyon
Subjects:
Lung cancer
Tobacco smoke
PTEN
microRNA
mir-301a
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023062527

Similar Items

Similar Items