Depressive symptoms in amnesic mild cognitive impairment: an FDG-PET/CT study
Introduction The detection in mild cognitive impairment (MCI) of metabolic alterations suggestive of depression and/or of evolution to dementia. Material and methods Sixty-nine MCI patients underwent clinical and imaging evaluation including position emission tomography/computed tomography with flu...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Termedia Publishing House
2022-06-01
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| Series: | Archives of Medical Science |
| Subjects: | |
| Online Access: | https://www.archivesofmedicalscience.com/Depressive-symptoms-in-amnesic-mild-cognitive-impairment-an-FDG-PET-CT-study,149717,0,2.html |
| _version_ | 1827620272863182848 |
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| author | Marco Mauri Clara Luigia Gobbo Lucia Princiotta Cariddi Ilaria Schiorlin Maurizio Versino |
| author_facet | Marco Mauri Clara Luigia Gobbo Lucia Princiotta Cariddi Ilaria Schiorlin Maurizio Versino |
| author_sort | Marco Mauri |
| collection | DOAJ |
| description | Introduction
The detection in mild cognitive impairment (MCI) of metabolic alterations suggestive of depression and/or of evolution to dementia.
Material and methods
Sixty-nine MCI patients underwent clinical and imaging evaluation including position emission tomography/computed tomography with fluorodeoxy-glucose (FDG-PET/CT).
Results
The metabolism mean values in parietal, temporal and pre-cuneus areas were lower in subjects who evolved to dementia, and in frontal and in anterior cingulate areas in depressed subjects. Abnormal metabolism values were higher in the frontal and parietal lobes, and in the precuneus in subjects who evolved to dementia independently from depression.
Conclusions
In MCI FDG-PET/CT abnormality patterns suggest the presence of depression or the evolution to dementia. |
| first_indexed | 2024-03-09T10:46:07Z |
| format | Article |
| id | doaj.art-0f9d7627026a4f92a3917d18ea3a8d64 |
| institution | Directory Open Access Journal |
| issn | 1734-1922 1896-9151 |
| language | English |
| last_indexed | 2024-03-09T10:46:07Z |
| publishDate | 2022-06-01 |
| publisher | Termedia Publishing House |
| record_format | Article |
| series | Archives of Medical Science |
| spelling | doaj.art-0f9d7627026a4f92a3917d18ea3a8d642023-12-01T10:02:33ZengTermedia Publishing HouseArchives of Medical Science1734-19221896-91512022-06-011841108111110.5114/aoms/149717149717Depressive symptoms in amnesic mild cognitive impairment: an FDG-PET/CT studyMarco Mauri0Clara Luigia Gobbo1Lucia Princiotta Cariddi2https://orcid.org/0000-0002-2265-1766Ilaria Schiorlin3Maurizio Versino4U.O.C. Neurologia e Stroke Unit, ASST Settelaghi, Ospedale di Circolo, Varese, ItalyNuclear Medicine Unit, ASST Settelaghi, Ospedale di Circolo, Varese, ItalyU.O.C. Neurologia e Stroke Unit, ASST Settelaghi, Ospedale di Circolo, Varese, ItalyNuclear Medicine Unit, ASST Settelaghi, Ospedale di Circolo, Varese, ItalyU.O.C. Neurologia e Stroke Unit, ASST Settelaghi, Ospedale di Circolo, Varese, ItalyIntroduction The detection in mild cognitive impairment (MCI) of metabolic alterations suggestive of depression and/or of evolution to dementia. Material and methods Sixty-nine MCI patients underwent clinical and imaging evaluation including position emission tomography/computed tomography with fluorodeoxy-glucose (FDG-PET/CT). Results The metabolism mean values in parietal, temporal and pre-cuneus areas were lower in subjects who evolved to dementia, and in frontal and in anterior cingulate areas in depressed subjects. Abnormal metabolism values were higher in the frontal and parietal lobes, and in the precuneus in subjects who evolved to dementia independently from depression. Conclusions In MCI FDG-PET/CT abnormality patterns suggest the presence of depression or the evolution to dementia.https://www.archivesofmedicalscience.com/Depressive-symptoms-in-amnesic-mild-cognitive-impairment-an-FDG-PET-CT-study,149717,0,2.htmlmild cognitive impairmentdementiadepressionposition emission tomography/computed tomography with fluorodeoxy-glucose |
| spellingShingle | Marco Mauri Clara Luigia Gobbo Lucia Princiotta Cariddi Ilaria Schiorlin Maurizio Versino Depressive symptoms in amnesic mild cognitive impairment: an FDG-PET/CT study Archives of Medical Science mild cognitive impairment dementia depression position emission tomography/computed tomography with fluorodeoxy-glucose |
| title | Depressive symptoms in amnesic mild cognitive impairment: an FDG-PET/CT study |
| title_full | Depressive symptoms in amnesic mild cognitive impairment: an FDG-PET/CT study |
| title_fullStr | Depressive symptoms in amnesic mild cognitive impairment: an FDG-PET/CT study |
| title_full_unstemmed | Depressive symptoms in amnesic mild cognitive impairment: an FDG-PET/CT study |
| title_short | Depressive symptoms in amnesic mild cognitive impairment: an FDG-PET/CT study |
| title_sort | depressive symptoms in amnesic mild cognitive impairment an fdg pet ct study |
| topic | mild cognitive impairment dementia depression position emission tomography/computed tomography with fluorodeoxy-glucose |
| url | https://www.archivesofmedicalscience.com/Depressive-symptoms-in-amnesic-mild-cognitive-impairment-an-FDG-PET-CT-study,149717,0,2.html |
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