Acinetobacter baumannii Infection in the Neonatal Intensive Care Unit
Background: To perform a prospective case control study of blood stream infection to determine the infection rate of Acine­tobac­ter baumannii and the risk factors associated with mortality."nMethods:   From February 2004 to January 2005, 57...
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2008-09-01
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| Series: | Iranian Journal of Public Health |
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| Online Access: | http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/11885.pdf&manuscript_id=11885 |
| _version_ | 1819138182831144960 |
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| author | AMK AL Jarousha IA El Qouqa AHN EL Jadba AS Al Afifi |
| author_facet | AMK AL Jarousha IA El Qouqa AHN EL Jadba AS Al Afifi |
| author_sort | AMK AL Jarousha |
| collection | DOAJ |
| description | Background: To perform a prospective case control study of blood stream infection to determine the infection rate of Acine­tobac­ter baumannii and the risk factors associated with mortality."nMethods:   From February 2004 to January 2005, 579 consecutive episodes of blood stream infection were obtained at two neo­na­tal intensive care units Al Nasser and Al Shifa hospitals in Gaza City. Forty (6.9%) isolates of A. baumannii were ob­tained from the neonates under 28 d. Most of the isolates (92%) were from hospitalized patients in the intensive care units."nResults: Community acquired infection was 8%.  Sixty three percent of the patients were males. The isolates of A. bauman­nii were resistant to commonly used antibiotics while being sensitive to meropenem (92.5%), imipenem (90%), chloram­pheni­col (80%), ciprofloxacin (75%), gentamicin (57.5%), ceftriaxone (50%), amikacin (37.5%), cefuroxime and ce­fo­taxime (35%). Over all crude mortality rate was 20% with much higher crude mortality among patients with noso­co­mial infec­tion.  Based on logistic regression, the following factors were statistically significant: weight < 1500g, age < 7 d, mean of hospitalization equal 20 days, antibiotic use, and mechanical ventilation, when compared to the control group (P< 0.05)."nConclusion:  Infection rate of nosocomial blood stream infection was considerable and alarming in neonatal intensive care unit infants and associated with a significant excess length of NICU stay and a significant economic burden.   |
| first_indexed | 2024-12-22T11:02:42Z |
| format | Article |
| id | doaj.art-0f9e9588e62645f3b79144346f9bfb80 |
| institution | Directory Open Access Journal |
| issn | 2251-6085 |
| language | English |
| last_indexed | 2024-12-22T11:02:42Z |
| publishDate | 2008-09-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Iranian Journal of Public Health |
| spelling | doaj.art-0f9e9588e62645f3b79144346f9bfb802022-12-21T18:28:26ZengTehran University of Medical SciencesIranian Journal of Public Health2251-60852008-09-01373107112Acinetobacter baumannii Infection in the Neonatal Intensive Care UnitAMK AL JaroushaIA El QouqaAHN EL JadbaAS Al AfifiBackground: To perform a prospective case control study of blood stream infection to determine the infection rate of Acine­tobac­ter baumannii and the risk factors associated with mortality."nMethods:   From February 2004 to January 2005, 579 consecutive episodes of blood stream infection were obtained at two neo­na­tal intensive care units Al Nasser and Al Shifa hospitals in Gaza City. Forty (6.9%) isolates of A. baumannii were ob­tained from the neonates under 28 d. Most of the isolates (92%) were from hospitalized patients in the intensive care units."nResults: Community acquired infection was 8%.  Sixty three percent of the patients were males. The isolates of A. bauman­nii were resistant to commonly used antibiotics while being sensitive to meropenem (92.5%), imipenem (90%), chloram­pheni­col (80%), ciprofloxacin (75%), gentamicin (57.5%), ceftriaxone (50%), amikacin (37.5%), cefuroxime and ce­fo­taxime (35%). Over all crude mortality rate was 20% with much higher crude mortality among patients with noso­co­mial infec­tion.  Based on logistic regression, the following factors were statistically significant: weight < 1500g, age < 7 d, mean of hospitalization equal 20 days, antibiotic use, and mechanical ventilation, when compared to the control group (P< 0.05)."nConclusion:  Infection rate of nosocomial blood stream infection was considerable and alarming in neonatal intensive care unit infants and associated with a significant excess length of NICU stay and a significant economic burden.  http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/11885.pdf&manuscript_id=11885Nosocomial infectionMultidrug resistanceNeonatal intensive care unitAcinetobacter baumannii |
| spellingShingle | AMK AL Jarousha IA El Qouqa AHN EL Jadba AS Al Afifi Acinetobacter baumannii Infection in the Neonatal Intensive Care Unit Iranian Journal of Public Health Nosocomial infection Multidrug resistance Neonatal intensive care unit Acinetobacter baumannii |
| title | Acinetobacter baumannii Infection in the Neonatal Intensive Care Unit |
| title_full | Acinetobacter baumannii Infection in the Neonatal Intensive Care Unit |
| title_fullStr | Acinetobacter baumannii Infection in the Neonatal Intensive Care Unit |
| title_full_unstemmed | Acinetobacter baumannii Infection in the Neonatal Intensive Care Unit |
| title_short | Acinetobacter baumannii Infection in the Neonatal Intensive Care Unit |
| title_sort | acinetobacter baumannii infection in the neonatal intensive care unit |
| topic | Nosocomial infection Multidrug resistance Neonatal intensive care unit Acinetobacter baumannii |
| url | http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/11885.pdf&manuscript_id=11885 |
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