Exosomal Carboxypeptidase E (CPE) and CPE-shRNA-Loaded Exosomes Regulate Metastatic Phenotype of Tumor Cells

Exosomal Carboxypeptidase E (CPE) and CPE-shRNA-Loaded Exosomes Regulate Metastatic Phenotype of Tumor Cells

Background: Exosomes promote tumor growth and metastasis through intercellular communication, although the mechanism remains elusive. Carboxypeptidase E (CPE) supports the progression of different cancers, including hepatocellular carcinoma (HCC). Here, we investigated whether CPE is the bioactive c...

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Bibliographic Details
Main Authors: Sangeetha Hareendran, Bassam Albraidy, Xuyu Yang, Aiyi Liu, Anne Breggia, Clark C. Chen, Y. Peng Loh
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:International Journal of Molecular Sciences
Subjects:
cancer proliferation
hepatocellular carcinoma
metastasis
engineered exosomes
diagnostic biomarker
cancer therapy
Online Access:https://www.mdpi.com/1422-0067/23/6/3113

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