Efficacy of quantitative diffusion MR imaging for the differentiation of malignant and benign lung lesions
INTRODUCTION: To assess lung lesions with quantitative diffusion MR imaging. METHODS: We retrospectively evaluated 120 patients with pulmonary lesions undergoing diffusion-weighted MR imaging. The ADC values of lung lesions were calculated and correlated with biopsy results. RESULTS: The ADC of...
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| Format: | Article |
| Language: | English |
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Van Yuzuncu Yil University, School of Medicine
2019-01-01
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| Series: | Van Tıp Dergisi |
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| Online Access: | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=vtd&un=VTD-25902 |
| _version_ | 1827611871530713088 |
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| author | Cihan Şimşek Necdet Poyraz |
| author_facet | Cihan Şimşek Necdet Poyraz |
| author_sort | Cihan Şimşek |
| collection | DOAJ |
| description | INTRODUCTION: To assess lung lesions with quantitative diffusion MR imaging.
METHODS: We retrospectively evaluated 120 patients with pulmonary lesions undergoing diffusion-weighted MR imaging. The ADC values of lung lesions were calculated and correlated with biopsy results.
RESULTS: The ADC of benign lung lesions (2.03+-0.09x10-3mm2/s) was significantly higher (P<0.001) than that of malignant lung tumors (1.11+-0.25x10-3mm2/s). Selection of 1.37x10-3mm2/s as a cut-off point for differentiating malignant from benign lung lesions revealed an area under the curve of 0.94, an accuracy of 87.5 %, a sensitivity of 94.9 %, and a specificity of of 73.1%. DISCUSSION AND CONCLUSION: Quantitative diffusion MR imaging may be used for differentiation of benign from malignant lung tumors. |
| first_indexed | 2024-03-09T08:13:12Z |
| format | Article |
| id | doaj.art-0fa32122d89c4382b17afb08d942a8f9 |
| institution | Directory Open Access Journal |
| issn | 2587-0351 |
| language | English |
| last_indexed | 2024-03-09T08:13:12Z |
| publishDate | 2019-01-01 |
| publisher | Van Yuzuncu Yil University, School of Medicine |
| record_format | Article |
| series | Van Tıp Dergisi |
| spelling | doaj.art-0fa32122d89c4382b17afb08d942a8f92023-12-02T22:48:29ZengVan Yuzuncu Yil University, School of MedicineVan Tıp Dergisi2587-03512019-01-0126161110.5505/vtd.2019.25902VTD-25902Efficacy of quantitative diffusion MR imaging for the differentiation of malignant and benign lung lesionsCihan Şimşek0Necdet Poyraz1Necmettin Erbakan University, Meram School of Medicine, Department of Radiology, Konya, TurkeyNecmettin Erbakan University, Meram School of Medicine, Department of Radiology, Konya, TurkeyINTRODUCTION: To assess lung lesions with quantitative diffusion MR imaging. METHODS: We retrospectively evaluated 120 patients with pulmonary lesions undergoing diffusion-weighted MR imaging. The ADC values of lung lesions were calculated and correlated with biopsy results. RESULTS: The ADC of benign lung lesions (2.03+-0.09x10-3mm2/s) was significantly higher (P<0.001) than that of malignant lung tumors (1.11+-0.25x10-3mm2/s). Selection of 1.37x10-3mm2/s as a cut-off point for differentiating malignant from benign lung lesions revealed an area under the curve of 0.94, an accuracy of 87.5 %, a sensitivity of 94.9 %, and a specificity of of 73.1%. DISCUSSION AND CONCLUSION: Quantitative diffusion MR imaging may be used for differentiation of benign from malignant lung tumors.https://jag.journalagent.com/z4/download_fulltext.asp?pdir=vtd&un=VTD-25902lung lesionsdiffusion-weighted mr imagingadc |
| spellingShingle | Cihan Şimşek Necdet Poyraz Efficacy of quantitative diffusion MR imaging for the differentiation of malignant and benign lung lesions Van Tıp Dergisi lung lesions diffusion-weighted mr imaging adc |
| title | Efficacy of quantitative diffusion MR imaging for the differentiation of malignant and benign lung lesions |
| title_full | Efficacy of quantitative diffusion MR imaging for the differentiation of malignant and benign lung lesions |
| title_fullStr | Efficacy of quantitative diffusion MR imaging for the differentiation of malignant and benign lung lesions |
| title_full_unstemmed | Efficacy of quantitative diffusion MR imaging for the differentiation of malignant and benign lung lesions |
| title_short | Efficacy of quantitative diffusion MR imaging for the differentiation of malignant and benign lung lesions |
| title_sort | efficacy of quantitative diffusion mr imaging for the differentiation of malignant and benign lung lesions |
| topic | lung lesions diffusion-weighted mr imaging adc |
| url | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=vtd&un=VTD-25902 |
| work_keys_str_mv | AT cihansimsek efficacyofquantitativediffusionmrimagingforthedifferentiationofmalignantandbenignlunglesions AT necdetpoyraz efficacyofquantitativediffusionmrimagingforthedifferentiationofmalignantandbenignlunglesions |