An emerging role for misfolded wild-type SOD1 in sporadic ALS pathogenesis

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder that targets motor neurons, leading to paralysis and death within a few years of disease onset. While several genes have been linked to the inheritable, or familial, form of ALS, much less is known about the cause(s) of spora...

Täydet tiedot

Bibliografiset tiedot
Päätekijät: Melissa S Rotunno, Daryl A Bosco
Aineistotyyppi: Artikkeli
Kieli:English
Julkaistu: Frontiers Media S.A. 2013-12-01
Sarja:Frontiers in Cellular Neuroscience
Aiheet:
Linkit:http://journal.frontiersin.org/Journal/10.3389/fncel.2013.00253/full