Functional Imaging of Proteolysis: Stromal and Inflammatory Cells Increase Tumor Proteolysis
The underlying basement membrane is degraded during progression of breast and colon carcinoma. Thus, we imaged degradation of a quenched fluorescent derivative of basement membrane type IV collagen (DQ-collagen IV) by living human breast and colon tumor spheroids. Proteolysis of DQ-collagen IV by HC...
Main Authors: | Mansoureh Sameni, Julie Dosescu, Kamiar Moin, Bonnie F. Sloane |
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Format: | Article |
Language: | English |
Published: |
SAGE Publications
2003-07-01
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Series: | Molecular Imaging |
Online Access: | https://doi.org/10.1162/15353500200303136 |
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