Rs145204276 and rs4759314 affect the prognosis of prostate cancer by modulating the GAS5/miR-1284/HMGB1 and HOTAIR/miR-22/HMGB1 signalling pathways

Rs145204276 and rs4759314 affect the prognosis of prostate cancer by modulating the GAS5/miR-1284/HMGB1 and HOTAIR/miR-22/HMGB1 signalling pathways

AbstractNon-coding RNAs play an important role in the pathogenesis of prostate cancer (PC). This study aims to characterize the role of GAS5 rs145204276 and HOTAIR rs4759314 polymorphisms in the pathogenesis of PC. Both INS allele of GAS5 rs145204276 and A allele of HOTAIR rs4759314 were identified...

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Bibliographic Details
Main Authors: Zhi-Hai Deng, Gan-Shen Yu, Bin Pan, Zhen-Hua Feng, Qiang Huang, Jian-Zhong Deng, Bo Chen, Shi-Kun Yang
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Artificial Cells, Nanomedicine, and Biotechnology
Subjects:
Prostate cancer
rs145204276
rs4759314
miR-1284
miR-22
GAS5
Online Access:https://www.tandfonline.com/doi/10.1080/21691401.2019.1709859

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