Early preclinical plasma protein biomarkers of brain trauma are influenced by early seizures and levetiracetam

Early preclinical plasma protein biomarkers of brain trauma are influenced by early seizures and levetiracetam

Abstract Objective We used the lateral fluid percussion injury (LFPI) model of moderate‐to‐severe traumatic brain injury (TBI) to identify early plasma biomarkers predicting injury, early post‐traumatic seizures or neuromotor functional recovery (neuroscores), considering the effect of levetiracetam...

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Bibliographic Details
Main Authors: Patricia G. Saletti, Wenzhu B. Mowrey, Wei Liu, Qianyun Li, Jesse McCullough, Roxanne Aniceto, I‐Hsuan Lin, Michael Eklund, Pablo M. Casillas‐Espinosa, Idrish Ali, Cesar Santana‐Gomez, Lisa Coles, Sandy R. Shultz, Nigel Jones, Richard Staba, Terence J. O'Brien, Solomon L. Moshé, Denes V. Agoston, Aristea S. Galanopoulou, for the EpiBioS4Rx Study Group
Format: Article
Language:English
Published: Wiley 2023-06-01
Series:Epilepsia Open
Subjects:
inflammation
lateral fluid percussion injury
levetiracetam
neuromotor recovery
tau
traumatic brain injury
Online Access:https://doi.org/10.1002/epi4.12738

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