Association of HLA-G 3′ UTR polymorphism and expression with the progression of cervical lesions in human papillomavirus 18 infections

Association of HLA-G 3′ UTR polymorphism and expression with the progression of cervical lesions in human papillomavirus 18 infections

Abstract Background Human leukocyte antigen (HLA)-G is an immune checkpoint molecule, which expression in cervical cancer cells enables them to escape immunosurveillance. To date, limited information has been published on the association of HLA-G genetic background in malignant cells with levels of...

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Bibliographic Details
Main Authors: Hui-Hui Xu, Xia Zhang, Hai-Hong Zheng, Qiu-Yue Han, Ai-Fen Lin, Wei-Hua Yan
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Infectious Agents and Cancer
Subjects:
Human leukocyte antigen-G
Polymorphism
Expression
Human papillomavirus 18
Precancerous cervical lesions
Cervical cancer
Online Access:http://link.springer.com/article/10.1186/s13027-018-0217-2

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