Proteomic analysis of anti-MRSA activity of caerin 1.1/1.9 in a murine skin infection model and their in vitro anti-biofilm effects against Acinetobacter baumannii

Proteomic analysis of anti-MRSA activity of caerin 1.1/1.9 in a murine skin infection model and their in vitro anti-biofilm effects against Acinetobacter baumannii

ABSTRACT Caerin 1 is a family of host defense peptides with antimicrobial properties originally isolated from the Australian tree frog. Both caerin 1.1 and caerin 1.9 have been demonstrated to inhibit infections caused by multiple antibiotic-resistant bacteria, both in vitro and in vivo. In this cur...

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Bibliographic Details
Main Authors: Pingping Zhang, Shuxian Tang, Quanlan Fu, Yuandong Luo, Junjie Li, Zhu Chen, Hejie Li, Guoying Ni, Tianfang Wang, Guoqiang Chen, Xiaosong Liu
Format: Article
Language:English
Published: American Society for Microbiology 2023-12-01
Series:Microbiology Spectrum
Subjects:
caerin 1 peptide
biofilm
proteomics
skin infection
Online Access:https://journals.asm.org/doi/10.1128/spectrum.04520-22

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