CD4+-mediated colitis in mice is independent of the GPR183 and GPR18 pathways

CD4+-mediated colitis in mice is independent of the GPR183 and GPR18 pathways

Colitis is characterized by an exacerbated intestinal immune response, but the genetic and other mechanisms regulating immune activation remain incompletely understood. In order to identify new pathways leading to colitis, we sought to identify genes with increased expression in the colons of patien...

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Bibliographic Details
Main Authors: Martina Dicker, Yingcong Li, Daniel A. Giles, Greet Verstichel, Viankail Cedillo Castelan, Gabriel Ascui-Gac, Ting-Fang Chou, Tamara Perez-Jeldres, Hilde Cheroutre, Mitchell Kronenberg
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Immunology
Subjects:
inflammatory bowel disease
chemokine receptor
gene expression
T cell transfer model
DSS model
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1034648/full

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