Analysis of the Exeter V40 femoral stem prosthesis fracture: systematic review and single centre case series

Aims: The Exeter V40 cemented polished tapered stem system has demonstrated excellent long-term outcomes. This paper presents a systematic review of the existing literature and reports on a large case series comparing implant fractures between the Exeter V40 series; 125 mm and conventional length st...

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Main Authors: Joshua W. Thompson, James Corbett, Daniel Bye, Adrian Jones, Elizabeth K. Tissingh, John Nolan
Format: Article
Language:English
Published: The British Editorial Society of Bone & Joint Surgery 2021-06-01
Series:Bone & Joint Open
Subjects:
Online Access:https://online.boneandjoint.org.uk/doi/epdf/10.1302/2633-1462.26.BJO-2021-0025.R1
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author Joshua W. Thompson
James Corbett
Daniel Bye
Adrian Jones
Elizabeth K. Tissingh
John Nolan
author_facet Joshua W. Thompson
James Corbett
Daniel Bye
Adrian Jones
Elizabeth K. Tissingh
John Nolan
author_sort Joshua W. Thompson
collection DOAJ
description Aims: The Exeter V40 cemented polished tapered stem system has demonstrated excellent long-term outcomes. This paper presents a systematic review of the existing literature and reports on a large case series comparing implant fractures between the Exeter V40 series; 125 mm and conventional length stem systems. Methods: A systematic literature search was performed adhering to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) criteria. In parallel, we performed a retrospective single centre study of Exeter V40 femoral stem prosthetic fractures between April 2003 and June 2020. Results: There are 25 reported cases of such prosthetic fractures confined to small case series and case reports within the literature. We report an additional 19 cases to the literature (mean age 66.3 years (SD 11.7); 12 (63%) females; BMI 32.9 kg/m2 (SD 5.9)). The mean time from index procedure to fracture was 7.8 years (SD 3.6; 2.5 to 16.3). Exeter V40 stem fracture incidence was 0.15% and 1.21% for primary and revision arthroplasty, respectively. Incidence was significantly higher in revision arthroplasty (p < 0.001) and 125 mm length stems compared to ≥ 150 mm length stems (1.25% vs 0.13%, respectively; p < 0.001). When comparing different stem length cohorts, 125 mm short-stems were associated with stem-body fractures (92% vs 29%; p = 0.0095), earlier time to fracture (6.2 years vs 11.0 years; p = 0.0018), younger patient age at time of fracture (62.7 years vs 72.6 years; p = 0.037), and female sex (75% vs 43%; p = 0.326). Conclusion: This complication remains rare, although we report a significantly higher incidence at up to 17 years follow-up than in the literature. Short 125 mm length Exeter V40 stems undoubtedly have a role in restoring anatomy and biomechanics in smaller femoral geometries, although the surgeon has to appreciate the higher risk of stem fracture and the associated predisposing factors which may necessitate particular attention to surgical technique and planning.
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spelling doaj.art-0fb7c38556024d4bb4bfa02aa3f3b9f72022-12-21T21:09:05ZengThe British Editorial Society of Bone & Joint SurgeryBone & Joint Open2633-14622021-06-012644345610.1302/2633-1462.26.BJO-2021-0025.R1Analysis of the Exeter V40 femoral stem prosthesis fracture: systematic review and single centre case seriesJoshua W. Thompson0James Corbett1Daniel Bye2Adrian Jones3Elizabeth K. Tissingh4John Nolan5Department of Trauma and Orthopaedic Surgery, Norfolk and Norwich University Hospital NHS Foundation Trust, Norwich, Norfolk, UKDepartment of Trauma and Orthopaedic Surgery, Norfolk and Norwich University Hospital NHS Foundation Trust, Norwich, Norfolk, UKDepartment of Trauma and Orthopaedic Surgery, Norfolk and Norwich University Hospital NHS Foundation Trust, Norwich, Norfolk, UKDepartment of Trauma and Orthopaedic Surgery, Norfolk and Norwich University Hospital NHS Foundation Trust, Norwich, Norfolk, UKDepartment of Trauma and Orthopaedic Surgery, Norfolk and Norwich University Hospital NHS Foundation Trust, Norwich, Norfolk, UKDepartment of Trauma and Orthopaedic Surgery, Norfolk and Norwich University Hospital NHS Foundation Trust, Norwich, Norfolk, UKAims: The Exeter V40 cemented polished tapered stem system has demonstrated excellent long-term outcomes. This paper presents a systematic review of the existing literature and reports on a large case series comparing implant fractures between the Exeter V40 series; 125 mm and conventional length stem systems. Methods: A systematic literature search was performed adhering to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) criteria. In parallel, we performed a retrospective single centre study of Exeter V40 femoral stem prosthetic fractures between April 2003 and June 2020. Results: There are 25 reported cases of such prosthetic fractures confined to small case series and case reports within the literature. We report an additional 19 cases to the literature (mean age 66.3 years (SD 11.7); 12 (63%) females; BMI 32.9 kg/m2 (SD 5.9)). The mean time from index procedure to fracture was 7.8 years (SD 3.6; 2.5 to 16.3). Exeter V40 stem fracture incidence was 0.15% and 1.21% for primary and revision arthroplasty, respectively. Incidence was significantly higher in revision arthroplasty (p < 0.001) and 125 mm length stems compared to ≥ 150 mm length stems (1.25% vs 0.13%, respectively; p < 0.001). When comparing different stem length cohorts, 125 mm short-stems were associated with stem-body fractures (92% vs 29%; p = 0.0095), earlier time to fracture (6.2 years vs 11.0 years; p = 0.0018), younger patient age at time of fracture (62.7 years vs 72.6 years; p = 0.037), and female sex (75% vs 43%; p = 0.326). Conclusion: This complication remains rare, although we report a significantly higher incidence at up to 17 years follow-up than in the literature. Short 125 mm length Exeter V40 stems undoubtedly have a role in restoring anatomy and biomechanics in smaller femoral geometries, although the surgeon has to appreciate the higher risk of stem fracture and the associated predisposing factors which may necessitate particular attention to surgical technique and planning.https://online.boneandjoint.org.uk/doi/epdf/10.1302/2633-1462.26.BJO-2021-0025.R1v40exeterfailurefracturestemincidence
spellingShingle Joshua W. Thompson
James Corbett
Daniel Bye
Adrian Jones
Elizabeth K. Tissingh
John Nolan
Analysis of the Exeter V40 femoral stem prosthesis fracture: systematic review and single centre case series
Bone & Joint Open
v40
exeter
failure
fracture
stem
incidence
title Analysis of the Exeter V40 femoral stem prosthesis fracture: systematic review and single centre case series
title_full Analysis of the Exeter V40 femoral stem prosthesis fracture: systematic review and single centre case series
title_fullStr Analysis of the Exeter V40 femoral stem prosthesis fracture: systematic review and single centre case series
title_full_unstemmed Analysis of the Exeter V40 femoral stem prosthesis fracture: systematic review and single centre case series
title_short Analysis of the Exeter V40 femoral stem prosthesis fracture: systematic review and single centre case series
title_sort analysis of the exeter v40 femoral stem prosthesis fracture systematic review and single centre case series
topic v40
exeter
failure
fracture
stem
incidence
url https://online.boneandjoint.org.uk/doi/epdf/10.1302/2633-1462.26.BJO-2021-0025.R1
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