Functional lung imaging using novel and emerging MRI techniques
Respiratory diseases are leading causes of death and disability in the world. While early diagnosis is key, this has proven difficult due to the lack of sensitive and non-invasive tools. Computed tomography is regarded as the gold standard for structural lung imaging but lacks functional information...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-04-01
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| Series: | Frontiers in Medicine |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2023.1060940/full |
| _version_ | 1797839987246366720 |
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| author | Chuan T. Foo Chuan T. Foo David Langton David Langton Bruce R. Thompson Francis Thien Francis Thien |
| author_facet | Chuan T. Foo Chuan T. Foo David Langton David Langton Bruce R. Thompson Francis Thien Francis Thien |
| author_sort | Chuan T. Foo |
| collection | DOAJ |
| description | Respiratory diseases are leading causes of death and disability in the world. While early diagnosis is key, this has proven difficult due to the lack of sensitive and non-invasive tools. Computed tomography is regarded as the gold standard for structural lung imaging but lacks functional information and involves significant radiation exposure. Lung magnetic resonance imaging (MRI) has historically been challenging due to its short T2 and low proton density. Hyperpolarised gas MRI is an emerging technique that is able to overcome these difficulties, permitting the functional and microstructural evaluation of the lung. Other novel imaging techniques such as fluorinated gas MRI, oxygen-enhanced MRI, Fourier decomposition MRI and phase-resolved functional lung imaging can also be used to interrogate lung function though they are currently at varying stages of development. This article provides a clinically focused review of these contrast and non-contrast MR imaging techniques and their current applications in lung disease. |
| first_indexed | 2024-04-09T16:07:01Z |
| format | Article |
| id | doaj.art-0fbc04d032734217b7eac2fea22ca43c |
| institution | Directory Open Access Journal |
| issn | 2296-858X |
| language | English |
| last_indexed | 2024-04-09T16:07:01Z |
| publishDate | 2023-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Medicine |
| spelling | doaj.art-0fbc04d032734217b7eac2fea22ca43c2023-04-25T04:51:28ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2023-04-011010.3389/fmed.2023.10609401060940Functional lung imaging using novel and emerging MRI techniquesChuan T. Foo0Chuan T. Foo1David Langton2David Langton3Bruce R. Thompson4Francis Thien5Francis Thien6Department of Respiratory Medicine, Eastern Health, Melbourne, VIC, AustraliaFaculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, VIC, AustraliaFaculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, VIC, AustraliaDepartment of Thoracic Medicine, Peninsula Health, Frankston, VIC, AustraliaMelbourne School of Health Science, Melbourne University, Melbourne, VIC, AustraliaDepartment of Respiratory Medicine, Eastern Health, Melbourne, VIC, AustraliaFaculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, VIC, AustraliaRespiratory diseases are leading causes of death and disability in the world. While early diagnosis is key, this has proven difficult due to the lack of sensitive and non-invasive tools. Computed tomography is regarded as the gold standard for structural lung imaging but lacks functional information and involves significant radiation exposure. Lung magnetic resonance imaging (MRI) has historically been challenging due to its short T2 and low proton density. Hyperpolarised gas MRI is an emerging technique that is able to overcome these difficulties, permitting the functional and microstructural evaluation of the lung. Other novel imaging techniques such as fluorinated gas MRI, oxygen-enhanced MRI, Fourier decomposition MRI and phase-resolved functional lung imaging can also be used to interrogate lung function though they are currently at varying stages of development. This article provides a clinically focused review of these contrast and non-contrast MR imaging techniques and their current applications in lung disease.https://www.frontiersin.org/articles/10.3389/fmed.2023.1060940/fullfluorinated gashyperpolarized gasmagnetic resonance imagingoxygen-enhancedtechniqueperfusion |
| spellingShingle | Chuan T. Foo Chuan T. Foo David Langton David Langton Bruce R. Thompson Francis Thien Francis Thien Functional lung imaging using novel and emerging MRI techniques Frontiers in Medicine fluorinated gas hyperpolarized gas magnetic resonance imaging oxygen-enhanced technique perfusion |
| title | Functional lung imaging using novel and emerging MRI techniques |
| title_full | Functional lung imaging using novel and emerging MRI techniques |
| title_fullStr | Functional lung imaging using novel and emerging MRI techniques |
| title_full_unstemmed | Functional lung imaging using novel and emerging MRI techniques |
| title_short | Functional lung imaging using novel and emerging MRI techniques |
| title_sort | functional lung imaging using novel and emerging mri techniques |
| topic | fluorinated gas hyperpolarized gas magnetic resonance imaging oxygen-enhanced technique perfusion |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2023.1060940/full |
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