Intronic Enhancer Is Essential for <i>Nr5a1</i> Expression in the Pituitary Gonadotrope and for Postnatal Development of Male Reproductive Organs in a Mouse Model

Intronic Enhancer Is Essential for <i>Nr5a1</i> Expression in the Pituitary Gonadotrope and for Postnatal Development of Male Reproductive Organs in a Mouse Model

Nuclear receptor subfamily 5 group A member 1 (NR5A1) is expressed in the pituitary gonadotrope and regulates their differentiation. Although several regulatory regions were implicated in <i>Nr5a1</i> gene expression in the pituitary gland, none of these regions have been verified using...

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Bibliographic Details
Main Authors: Yuichi Shima, Kanako Miyabayashi, Takami Mori, Koji Ono, Mizuki Kajimoto, Hae Lim Cho, Hitomi Tsuchida, Yoshihisa Uenoyama, Hiroko Tsukamura, Kentaro Suzuki, Man Ho Choi, Kazunori Toida
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:International Journal of Molecular Sciences
Subjects:
NR5A1
enhancer
pituitary gonadotrope
luteinizing hormone
follicle-stimulating hormone
Online Access:https://www.mdpi.com/1422-0067/24/1/192

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