Evaluation of the optic nerve head vessel density in patients with limited scleroderma
Objectives: To investigate the optical coherence tomography angiography (OCTA) parameters of the optic nerve head and peripapillary retina and to assess macular and peripapillary retinal nerve fiber layer (RNFL) thickness by using spectral-domain optical coherence tomography (SD-OCT) in patients wit...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2021-02-01
|
| Series: | Therapeutic Advances in Ophthalmology |
| Online Access: | https://doi.org/10.1177/2515841421995387 |
| _version_ | 1818864330671652864 |
|---|---|
| author | Hilal Kılınç Hekimsoy Mehmet Ali Şekeroğlu Ali Mert Koçer Vedat Hekimsoy Ali Akdoğan |
| author_facet | Hilal Kılınç Hekimsoy Mehmet Ali Şekeroğlu Ali Mert Koçer Vedat Hekimsoy Ali Akdoğan |
| author_sort | Hilal Kılınç Hekimsoy |
| collection | DOAJ |
| description | Objectives: To investigate the optical coherence tomography angiography (OCTA) parameters of the optic nerve head and peripapillary retina and to assess macular and peripapillary retinal nerve fiber layer (RNFL) thickness by using spectral-domain optical coherence tomography (SD-OCT) in patients with limited scleroderma and to compare these results with those of healthy control subjects. Materials and Methods: 42 patients with a confirmed diagnosis of limited scleroderma and 32 age- and sex-matched healthy control subjects were included in the study. OCTA was performed for the radial peripapillary capillary plexus (RPCP) whole image, inside disc, and peripapillary vessel densities in all participants with XR Avanti AngioVue OCTA (Optovue, Fremont, California, USA). OCT images were obtained with Spectralis OCT with eye-tracking dual-beam technology (Heidelberg Engineering GmbH, Heidelberg, Germany), and peripapillary RNFL thickness was evaluated with circle program. The data from the right eyes of all participants were used for statistical analysis. Results: No significant difference was found between the radial RPCP whole image, inside disc, and peripapillary vessel density values or the RNFL parameters of the scleroderma patients when compared with the controls ( p > 0.05 for all). Conclusion: Decreased peripapillary vessel density on OCTA, which can be an early sign of glaucoma, could not be observed in scleroderma patients in this study. However, further long-term studies are still needed to identify glaucoma tendency in patients with scleroderma before clinically detectable glaucoma. |
| first_indexed | 2024-12-19T10:29:57Z |
| format | Article |
| id | doaj.art-0fc009fdda1f45b3b6d1657298ad4f32 |
| institution | Directory Open Access Journal |
| issn | 2515-8414 |
| language | English |
| last_indexed | 2024-12-19T10:29:57Z |
| publishDate | 2021-02-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Therapeutic Advances in Ophthalmology |
| spelling | doaj.art-0fc009fdda1f45b3b6d1657298ad4f322022-12-21T20:25:47ZengSAGE PublishingTherapeutic Advances in Ophthalmology2515-84142021-02-011310.1177/2515841421995387Evaluation of the optic nerve head vessel density in patients with limited sclerodermaHilal Kılınç HekimsoyMehmet Ali ŞekeroğluAli Mert KoçerVedat HekimsoyAli AkdoğanObjectives: To investigate the optical coherence tomography angiography (OCTA) parameters of the optic nerve head and peripapillary retina and to assess macular and peripapillary retinal nerve fiber layer (RNFL) thickness by using spectral-domain optical coherence tomography (SD-OCT) in patients with limited scleroderma and to compare these results with those of healthy control subjects. Materials and Methods: 42 patients with a confirmed diagnosis of limited scleroderma and 32 age- and sex-matched healthy control subjects were included in the study. OCTA was performed for the radial peripapillary capillary plexus (RPCP) whole image, inside disc, and peripapillary vessel densities in all participants with XR Avanti AngioVue OCTA (Optovue, Fremont, California, USA). OCT images were obtained with Spectralis OCT with eye-tracking dual-beam technology (Heidelberg Engineering GmbH, Heidelberg, Germany), and peripapillary RNFL thickness was evaluated with circle program. The data from the right eyes of all participants were used for statistical analysis. Results: No significant difference was found between the radial RPCP whole image, inside disc, and peripapillary vessel density values or the RNFL parameters of the scleroderma patients when compared with the controls ( p > 0.05 for all). Conclusion: Decreased peripapillary vessel density on OCTA, which can be an early sign of glaucoma, could not be observed in scleroderma patients in this study. However, further long-term studies are still needed to identify glaucoma tendency in patients with scleroderma before clinically detectable glaucoma.https://doi.org/10.1177/2515841421995387 |
| spellingShingle | Hilal Kılınç Hekimsoy Mehmet Ali Şekeroğlu Ali Mert Koçer Vedat Hekimsoy Ali Akdoğan Evaluation of the optic nerve head vessel density in patients with limited scleroderma Therapeutic Advances in Ophthalmology |
| title | Evaluation of the optic nerve head vessel density in patients with limited scleroderma |
| title_full | Evaluation of the optic nerve head vessel density in patients with limited scleroderma |
| title_fullStr | Evaluation of the optic nerve head vessel density in patients with limited scleroderma |
| title_full_unstemmed | Evaluation of the optic nerve head vessel density in patients with limited scleroderma |
| title_short | Evaluation of the optic nerve head vessel density in patients with limited scleroderma |
| title_sort | evaluation of the optic nerve head vessel density in patients with limited scleroderma |
| url | https://doi.org/10.1177/2515841421995387 |
| work_keys_str_mv | AT hilalkılınchekimsoy evaluationoftheopticnerveheadvesseldensityinpatientswithlimitedscleroderma AT mehmetalisekeroglu evaluationoftheopticnerveheadvesseldensityinpatientswithlimitedscleroderma AT alimertkocer evaluationoftheopticnerveheadvesseldensityinpatientswithlimitedscleroderma AT vedathekimsoy evaluationoftheopticnerveheadvesseldensityinpatientswithlimitedscleroderma AT aliakdogan evaluationoftheopticnerveheadvesseldensityinpatientswithlimitedscleroderma |