The area under the effect curve as an efficacy determinant for anti‐infectives
Abstract Pharmacokinetic/pharmacodynamic (PK/PD) indices making use of area under the curve, maximum concentration, and the duration that in vivo drug concentration is maintained above a critical level are commonly applied to clinical dose prediction from animal efficacy experiments in the infectiou...
Main Authors: | Chao Chen, Silvia Maria Lavezzi, Laura Iavarone |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2022-08-01
|
Series: | CPT: Pharmacometrics & Systems Pharmacology |
Online Access: | https://doi.org/10.1002/psp4.12811 |
Similar Items
-
Characteristics and calculations of paired vancomycin measurements for determination of 24-h area-under-curve (AUC)
by: Yutao Deng, et al.
Published: (2023-03-01) -
Exact Probability Distribution for the ROC Area under Curve
by: Joakim Ekström, et al.
Published: (2023-03-01) -
Matching fingerface based on area under the highest peaks curve
by: Elmadani, Ahmed Baba, et al.
Published: (2010) -
Ratio of lymphocyte to monocyte area under the curve as a novel predictive factor for severe infection in multiple sclerosis
by: Junichiro Takahashi, et al.
Published: (2023-02-01) -
Comparison of area under the curve in various models of diabetic rats receiving chronic medication
by: Keng-Fan Liu, et al.
Published: (2020-01-01)