Sphingosine-1-Phosphate Receptor Modulators and Oligodendroglial Cells: Beyond Immunomodulation

Sphingosine-1-Phosphate Receptor Modulators and Oligodendroglial Cells: Beyond Immunomodulation

Multiple sclerosis (MS) is an autoimmune inflammatory disease characterized by demyelination, axonal loss, and synaptic impairment in the central nervous system (CNS). The available therapies aim to reduce the severity of the pathology during the early inflammatory stages, but they are not effective...

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Bibliographic Details
Main Authors: Alessandra Roggeri, Melissa Schepers, Assia Tiane, Ben Rombaut, Lieve van Veggel, Niels Hellings, Jos Prickaerts, Anna Pittaluga, Tim Vanmierlo
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:International Journal of Molecular Sciences
Subjects:
Sphingosine-1-phosphate receptor modulators
OPC
oligodendrocyte
demyelination
multiple sclerosis
Online Access:https://www.mdpi.com/1422-0067/21/20/7537

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