Cyclic Diguanylate Regulates Virulence Factor Genes via Multiple Riboswitches in <italic toggle="yes">Clostridium difficile</italic>

Cyclic Diguanylate Regulates Virulence Factor Genes via Multiple Riboswitches in <italic toggle="yes">Clostridium difficile</italic>

ABSTRACT The intracellular signaling molecule cyclic diguanylate (c-di-GMP) regulates many processes in bacteria, with a central role in controlling the switch between motile and nonmotile lifestyles. Recent work has shown that in Clostridium difficile (also called Clostridioides difficile), c-di-GM...

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Bibliographic Details
Main Authors: Robert W. McKee, Carissa K. Harvest, Rita Tamayo
Format: Article
Language:English
Published: American Society for Microbiology 2018-10-01
Series:mSphere
Subjects:
Clostridium difficile
biofilms
c-di-GMP
cyclic diguanylate
flagellar motility
riboswitch
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00423-18

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