Unsuppressed HIV infection impairs T cell responses to SARS-CoV-2 infection and abrogates T cell cross-recognition

Unsuppressed HIV infection impairs T cell responses to SARS-CoV-2 infection and abrogates T cell cross-recognition

In some instances, unsuppressed HIV has been associated with severe COVID-19 disease, but the mechanisms underpinning this susceptibility are still unclear. Here, we assessed the impact of HIV infection on the quality and epitope specificity of SARS-CoV-2 T cell responses in the first wave and secon...

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Bibliographic Details
Main Authors: Thandeka Nkosi, Caroline Chasara, Andrea O Papadopoulos, Tiza L Nguni, Farina Karim, Mahomed-Yunus S Moosa, Inbal Gazy, Kondwani Jambo, COMMIT-KZN-Team, Willem Hanekom, Alex Sigal, Zaza M Ndhlovu
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-07-01
Series:eLife
Subjects:
SARS-CoV-2
HIV
T cell responses
SARS-CoV-2 variants
Online Access:https://elifesciences.org/articles/78374

Internet

https://elifesciences.org/articles/78374

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