Clinical features of epileptic syndrome and alteration of NMDAand of AMPA-receptors of glutamate in the pathogenesis of the disease in the patients with supratentorial meningiomas of the brain
Forty three patients with supratentorial meningiomas were under examination. A significant increase of the level of autoantibodies to the GluR1 -subunit of the AMPA-receptors of glutamate was seen in the patients with meningiomas with epileptic syndrome. The maximal level of the autoantibodies to th...
| Main Authors: | , , |
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| Format: | Article |
| Language: | Russian |
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Academician I.P. Pavlov First St. Petersburg State Medical University
2018-12-01
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| Series: | Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова |
| Subjects: | |
| Online Access: | https://www.sci-notes.ru/jour/article/view/294 |
| Summary: | Forty three patients with supratentorial meningiomas were under examination. A significant increase of the level of autoantibodies to the GluR1 -subunit of the AMPA-receptors of glutamate was seen in the patients with meningiomas with epileptic syndrome. The maximal level of the autoantibodies to the GluR1-subunit of the AMPA-receptors of glutamate is registreted under the effect of the tumor on the frontal and temporal lobes. |
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| ISSN: | 1607-4181 2541-8807 |