Clinical features of epileptic syndrome and alteration of NMDAand of AMPA-receptors of glutamate in the pathogenesis of the disease in the patients with supratentorial meningiomas of the brain
Forty three patients with supratentorial meningiomas were under examination. A significant increase of the level of autoantibodies to the GluR1 -subunit of the AMPA-receptors of glutamate was seen in the patients with meningiomas with epileptic syndrome. The maximal level of the autoantibodies to th...
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| Format: | Article |
| Language: | Russian |
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Academician I.P. Pavlov First St. Petersburg State Medical University
2018-12-01
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| Series: | Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова |
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| Online Access: | https://www.sci-notes.ru/jour/article/view/294 |
| _version_ | 1826560841617506304 |
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| author | V. N. Ochkolyas A. A. Skoromets A. F. Gurchin |
| author_facet | V. N. Ochkolyas A. A. Skoromets A. F. Gurchin |
| author_sort | V. N. Ochkolyas |
| collection | DOAJ |
| description | Forty three patients with supratentorial meningiomas were under examination. A significant increase of the level of autoantibodies to the GluR1 -subunit of the AMPA-receptors of glutamate was seen in the patients with meningiomas with epileptic syndrome. The maximal level of the autoantibodies to the GluR1-subunit of the AMPA-receptors of glutamate is registreted under the effect of the tumor on the frontal and temporal lobes. |
| first_indexed | 2024-03-12T04:46:37Z |
| format | Article |
| id | doaj.art-0fc94cdcedca44d09d8aa3bf83c6696b |
| institution | Directory Open Access Journal |
| issn | 1607-4181 2541-8807 |
| language | Russian |
| last_indexed | 2025-03-14T09:22:41Z |
| publishDate | 2018-12-01 |
| publisher | Academician I.P. Pavlov First St. Petersburg State Medical University |
| record_format | Article |
| series | Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова |
| spelling | doaj.art-0fc94cdcedca44d09d8aa3bf83c6696b2025-03-02T11:44:09ZrusAcademician I.P. Pavlov First St. Petersburg State Medical UniversityУчёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова1607-41812541-88072018-12-01202313510.24884/1607-4181-2013-20-2-31-35277Clinical features of epileptic syndrome and alteration of NMDAand of AMPA-receptors of glutamate in the pathogenesis of the disease in the patients with supratentorial meningiomas of the brainV. N. Ochkolyas0A. A. Skoromets1A. F. Gurchin2Санкт-Петербургский государственный медицинский университет имени академика И. П. Павлова; Институт мозга человека имени Н. П. Бехтеревой РАН, Санкт-ПетербургСанкт-Петербургский государственный медицинский университет имени академика И. П. Павлова; Институт мозга человека имени Н. П. Бехтеревой РАН, Санкт-ПетербургСанкт-Петербургский государственный медицинский университет имени академика И. П. Павлова; Институт мозга человека имени Н. П. Бехтеревой РАН, Санкт-ПетербургForty three patients with supratentorial meningiomas were under examination. A significant increase of the level of autoantibodies to the GluR1 -subunit of the AMPA-receptors of glutamate was seen in the patients with meningiomas with epileptic syndrome. The maximal level of the autoantibodies to the GluR1-subunit of the AMPA-receptors of glutamate is registreted under the effect of the tumor on the frontal and temporal lobes.https://www.sci-notes.ru/jour/article/view/294epileptic syndromeampa-receptors of glutamatenmda-glutamate receptorsmeningiomas |
| spellingShingle | V. N. Ochkolyas A. A. Skoromets A. F. Gurchin Clinical features of epileptic syndrome and alteration of NMDAand of AMPA-receptors of glutamate in the pathogenesis of the disease in the patients with supratentorial meningiomas of the brain Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова epileptic syndrome ampa-receptors of glutamate nmda-glutamate receptors meningiomas |
| title | Clinical features of epileptic syndrome and alteration of NMDAand of AMPA-receptors of glutamate in the pathogenesis of the disease in the patients with supratentorial meningiomas of the brain |
| title_full | Clinical features of epileptic syndrome and alteration of NMDAand of AMPA-receptors of glutamate in the pathogenesis of the disease in the patients with supratentorial meningiomas of the brain |
| title_fullStr | Clinical features of epileptic syndrome and alteration of NMDAand of AMPA-receptors of glutamate in the pathogenesis of the disease in the patients with supratentorial meningiomas of the brain |
| title_full_unstemmed | Clinical features of epileptic syndrome and alteration of NMDAand of AMPA-receptors of glutamate in the pathogenesis of the disease in the patients with supratentorial meningiomas of the brain |
| title_short | Clinical features of epileptic syndrome and alteration of NMDAand of AMPA-receptors of glutamate in the pathogenesis of the disease in the patients with supratentorial meningiomas of the brain |
| title_sort | clinical features of epileptic syndrome and alteration of nmdaand of ampa receptors of glutamate in the pathogenesis of the disease in the patients with supratentorial meningiomas of the brain |
| topic | epileptic syndrome ampa-receptors of glutamate nmda-glutamate receptors meningiomas |
| url | https://www.sci-notes.ru/jour/article/view/294 |
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