Analysis of risk factors of hepatocellular carcinoma and establishment of a clinical prognosis model
Liver cancer is a common malignancy of the digestive system. Hepatocellular carcinoma (HCC) accounts for the most majority of these tumors and it has brought a heavy medical burden to underdeveloped countries and regions. Many factors affect the prognosis of HCC patients, however, there is no specif...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2023-03-01
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| Series: | Frontiers in Oncology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2023.1067353/full |
| _version_ | 1797866072003575808 |
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| author | Xin-Yu Ge Ming-Chen Sun Tian-Yi Wang Xi-Min Wang Gang Liu Tao Yang Yi-Ming Lu Wei Wang |
| author_facet | Xin-Yu Ge Ming-Chen Sun Tian-Yi Wang Xi-Min Wang Gang Liu Tao Yang Yi-Ming Lu Wei Wang |
| author_sort | Xin-Yu Ge |
| collection | DOAJ |
| description | Liver cancer is a common malignancy of the digestive system. Hepatocellular carcinoma (HCC) accounts for the most majority of these tumors and it has brought a heavy medical burden to underdeveloped countries and regions. Many factors affect the prognosis of HCC patients, however, there is no specific statistical model to predict the survival time of clinical patients. This study derived a risk factor signature of HCC and reliable clinical prediction model by statistically analyzing The Surveillance, Epidemiology, and End Results (SEER) database patient information using an open source package in the python environment. |
| first_indexed | 2024-04-09T23:18:11Z |
| format | Article |
| id | doaj.art-0fc9e8301e5e4f3c9ef7345daebba380 |
| institution | Directory Open Access Journal |
| issn | 2234-943X |
| language | English |
| last_indexed | 2024-04-09T23:18:11Z |
| publishDate | 2023-03-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Oncology |
| spelling | doaj.art-0fc9e8301e5e4f3c9ef7345daebba3802023-03-22T04:36:43ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2023-03-011310.3389/fonc.2023.10673531067353Analysis of risk factors of hepatocellular carcinoma and establishment of a clinical prognosis modelXin-Yu Ge0Ming-Chen Sun1Tian-Yi Wang2Xi-Min Wang3Gang Liu4Tao Yang5Yi-Ming Lu6Wei Wang7First Affiliated Hospital of Jinzhou Medical University, Jinzhou, ChinaFirst Affiliated Hospital of Jinzhou Medical University, Jinzhou, ChinaFirst Affiliated Hospital of Jinzhou Medical University, Jinzhou, ChinaJinzhou Medical University, Jinzhou, Liaoning, ChinaJinzhou Medical University, Jinzhou, Liaoning, ChinaFirst Affiliated Hospital of Jinzhou Medical University, Jinzhou, ChinaJinzhou Medical University, Jinzhou, Liaoning, ChinaFirst Affiliated Hospital of Jinzhou Medical University, Jinzhou, ChinaLiver cancer is a common malignancy of the digestive system. Hepatocellular carcinoma (HCC) accounts for the most majority of these tumors and it has brought a heavy medical burden to underdeveloped countries and regions. Many factors affect the prognosis of HCC patients, however, there is no specific statistical model to predict the survival time of clinical patients. This study derived a risk factor signature of HCC and reliable clinical prediction model by statistically analyzing The Surveillance, Epidemiology, and End Results (SEER) database patient information using an open source package in the python environment.https://www.frontiersin.org/articles/10.3389/fonc.2023.1067353/fullHCC (hepatic cellular carcinoma)SEER (Surveillance Epidemiology and End Results) databasemachine learning - MLrisk factorsrandom survival forest model |
| spellingShingle | Xin-Yu Ge Ming-Chen Sun Tian-Yi Wang Xi-Min Wang Gang Liu Tao Yang Yi-Ming Lu Wei Wang Analysis of risk factors of hepatocellular carcinoma and establishment of a clinical prognosis model Frontiers in Oncology HCC (hepatic cellular carcinoma) SEER (Surveillance Epidemiology and End Results) database machine learning - ML risk factors random survival forest model |
| title | Analysis of risk factors of hepatocellular carcinoma and establishment of a clinical prognosis model |
| title_full | Analysis of risk factors of hepatocellular carcinoma and establishment of a clinical prognosis model |
| title_fullStr | Analysis of risk factors of hepatocellular carcinoma and establishment of a clinical prognosis model |
| title_full_unstemmed | Analysis of risk factors of hepatocellular carcinoma and establishment of a clinical prognosis model |
| title_short | Analysis of risk factors of hepatocellular carcinoma and establishment of a clinical prognosis model |
| title_sort | analysis of risk factors of hepatocellular carcinoma and establishment of a clinical prognosis model |
| topic | HCC (hepatic cellular carcinoma) SEER (Surveillance Epidemiology and End Results) database machine learning - ML risk factors random survival forest model |
| url | https://www.frontiersin.org/articles/10.3389/fonc.2023.1067353/full |
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