Is there still room for novelty, in histochemical papers?

<p>Histochemistry continues to be widely applied in biomedical research, being nowadays mostly addressed to detect and locate single molecules or molecular complexes inside cells and tissues, and to relate structural organization and function at the high resolution of the more advanced microsc...

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Main Author: Carlo Pellicciari
Format: Article
Language:English
Published: PAGEPress Publications 2016-12-01
Series:European Journal of Histochemistry
Subjects:
Online Access:http://www.ejh.it/index.php/ejh/article/view/2758
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author Carlo Pellicciari
author_facet Carlo Pellicciari
author_sort Carlo Pellicciari
collection DOAJ
description <p>Histochemistry continues to be widely applied in biomedical research, being nowadays mostly addressed to detect and locate single molecules or molecular complexes inside cells and tissues, and to relate structural organization and function at the high resolution of the more advanced microscopical techniques. In the attempt to see whether histochemical novelties may be found in the recent literature, the articles published in the European Journal of Histochemistry in the period 2014-2016 have been reviewed. In the majority of the published papers, standardized methods have been preferred by scientists to make their results reliably comparable with the data in the literature, but  many papers (approximately one fourth of the published articles) described novel histochemical methods and procedures.  It is worth noting that there is a growing interest for minimally-invasive <em>in vivo</em> techniques (magnetic resonance imaging, autofluorescence spectroscopy) which may parallel conventional  histochemical analyses to obtain information not only on the morphological features of living organs and tissues, but also on their functional, biophysical and molecular characteristics. Thanks to this unceasing methodological refinement, histochemistry will continue to provide innovative applications in the biomedical field.</p>
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spelling doaj.art-0fcd7e0461df4dd5839c9a03829dd6102022-12-22T03:17:24ZengPAGEPress PublicationsEuropean Journal of Histochemistry1121-760X2038-83062016-12-0160410.4081/ejh.2016.27581537Is there still room for novelty, in histochemical papers?Carlo Pellicciari0University of Pavia<p>Histochemistry continues to be widely applied in biomedical research, being nowadays mostly addressed to detect and locate single molecules or molecular complexes inside cells and tissues, and to relate structural organization and function at the high resolution of the more advanced microscopical techniques. In the attempt to see whether histochemical novelties may be found in the recent literature, the articles published in the European Journal of Histochemistry in the period 2014-2016 have been reviewed. In the majority of the published papers, standardized methods have been preferred by scientists to make their results reliably comparable with the data in the literature, but  many papers (approximately one fourth of the published articles) described novel histochemical methods and procedures.  It is worth noting that there is a growing interest for minimally-invasive <em>in vivo</em> techniques (magnetic resonance imaging, autofluorescence spectroscopy) which may parallel conventional  histochemical analyses to obtain information not only on the morphological features of living organs and tissues, but also on their functional, biophysical and molecular characteristics. Thanks to this unceasing methodological refinement, histochemistry will continue to provide innovative applications in the biomedical field.</p>http://www.ejh.it/index.php/ejh/article/view/2758Histochemistry
spellingShingle Carlo Pellicciari
Is there still room for novelty, in histochemical papers?
European Journal of Histochemistry
Histochemistry
title Is there still room for novelty, in histochemical papers?
title_full Is there still room for novelty, in histochemical papers?
title_fullStr Is there still room for novelty, in histochemical papers?
title_full_unstemmed Is there still room for novelty, in histochemical papers?
title_short Is there still room for novelty, in histochemical papers?
title_sort is there still room for novelty in histochemical papers
topic Histochemistry
url http://www.ejh.it/index.php/ejh/article/view/2758
work_keys_str_mv AT carlopellicciari istherestillroomfornoveltyinhistochemicalpapers