Facile Syntheses and Molecular-Docking of Novel Substituted 3,4-Dimethyl-1H-pyrrole-2-carboxamide/carbohydrazide Analogues with Antimicrobial and Antifungal Properties

Facile Syntheses and Molecular-Docking of Novel Substituted 3,4-Dimethyl-1H-pyrrole-2-carboxamide/carbohydrazide Analogues with Antimicrobial and Antifungal Properties

The article describes the use of facile one-pot, high-yielding reactions to synthesize substituted 3,4-dimethyl-1H-pyrrole-2-carboxamides 3a–m and carbohydrazide analogues 5a–l as potential antifungal and antimicrobial agents. The structural identity and purity of the synthesized compounds were assi...

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Bibliographic Details
Main Authors: Jitendra D. Bhosale, Rajesh Dabur, Gopal P. Jadhav, R. S. Bendre
Format: Article
Language:English
Published: MDPI AG 2018-04-01
Series:Molecules
Subjects:
carboxamide
carbohydrazine
antibacterial
antifungal
molecular docking
Schiff base
NMR
IR
Online Access:http://www.mdpi.com/1420-3049/23/4/875

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