Asymmetric silane reduction of ketones and β-Keto esters catalyzed by a chiral azolium/iridium system in the presence of a base in methanol at room temperature
Asymmetric silane reduction of ketones catalyzed by a system comprising a chiral azolium salt 1 and [Ir(cod)2]BF4 (2) in the presence of a base in methanol was achieved at room temperature within 2 h. Implementing a “pre-mixing” experimental procedure improved the efficiency of the catalytic reactio...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2022-01-01
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| Series: | Results in Chemistry |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211715622000832 |