The Subcellular Localisation of the Human Papillomavirus (HPV) 16 E7 Protein in Cervical Cancer Cells and Its Perturbation by RNA Aptamers

The Subcellular Localisation of the Human Papillomavirus (HPV) 16 E7 Protein in Cervical Cancer Cells and Its Perturbation by RNA Aptamers

Human papillomavirus (HPV) is the most common viral infection of the reproductive tract, affecting both men and women. High-risk oncogenic types are responsible for almost 90% of anogenital and oropharyngeal cancers including cervical cancer. Some of the HPV “early” genes, particularly E6 and E7, ar...

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Bibliographic Details
Main Authors: Özlem Cesur, Clare Nicol, Helen Groves, Jamel Mankouri, George Eric Blair, Nicola J. Stonehouse
Format: Article
Language:English
Published: MDPI AG 2015-06-01
Series:Viruses
Subjects:
HPV16 E7
SELEX
RNA aptamers
cell surface localisation
ER retention
Online Access:http://www.mdpi.com/1999-4915/7/7/2780

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