Research Progress on Antitumor Mechanism and Structure-activity Relationship of Plant Polysaccharides

Plant polysaccharides, one of the main sources of natural polysaccharides, has significant antitumor activity and are potentially exploitable in the field of food and medicine. This paper systematically summarizes the anti-tumor mechanism and structure-activity relationships of plant polysaccharides...

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Main Authors: Guifeng ZHANG, Chuang LIU, Guangdong LIU, Rentang ZHANG
Format: Article
Language:zho
Published: The editorial department of Science and Technology of Food Industry 2023-04-01
Series:Shipin gongye ke-ji
Subjects:
Online Access:http://www.spgykj.com/cn/article/doi/10.13386/j.issn1002-0306.2022050063
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author Guifeng ZHANG
Chuang LIU
Guangdong LIU
Rentang ZHANG
author_facet Guifeng ZHANG
Chuang LIU
Guangdong LIU
Rentang ZHANG
author_sort Guifeng ZHANG
collection DOAJ
description Plant polysaccharides, one of the main sources of natural polysaccharides, has significant antitumor activity and are potentially exploitable in the field of food and medicine. This paper systematically summarizes the anti-tumor mechanism and structure-activity relationships of plant polysaccharides, focusing on three perspectives: Inhibition of tumor cell growth, enhancement of immune regulation, and inhibition of tumor cell invasion and metastasis. The functional-structural relationships of plant polysaccharides are further dissected based on their molecular weight, glycosidic bond types and monosaccharide composition, modified modifications and advanced structures. In this paper, the antitumor activity and structure-bioactivity relationships of plant polysaccharides are systematically summarized to provide a reference for discovering its new breakthroughs and further development.
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spelling doaj.art-0fd730dbcada41daba0d70724ae2ad842023-03-23T01:41:47ZzhoThe editorial department of Science and Technology of Food IndustryShipin gongye ke-ji1002-03062023-04-0144742843710.13386/j.issn1002-0306.20220500632022050063-7Research Progress on Antitumor Mechanism and Structure-activity Relationship of Plant PolysaccharidesGuifeng ZHANG0Chuang LIU1Guangdong LIU2Rentang ZHANG3College of Food Science and Engineering, Shandong Agricultural University, Taian 271018, ChinaCollege of Food Science and Engineering, Shandong Agricultural University, Taian 271018, ChinaShandong Land Rural Revitalization Group Co., Ltd., Jinan 251000, ChinaCollege of Food Science and Engineering, Shandong Agricultural University, Taian 271018, ChinaPlant polysaccharides, one of the main sources of natural polysaccharides, has significant antitumor activity and are potentially exploitable in the field of food and medicine. This paper systematically summarizes the anti-tumor mechanism and structure-activity relationships of plant polysaccharides, focusing on three perspectives: Inhibition of tumor cell growth, enhancement of immune regulation, and inhibition of tumor cell invasion and metastasis. The functional-structural relationships of plant polysaccharides are further dissected based on their molecular weight, glycosidic bond types and monosaccharide composition, modified modifications and advanced structures. In this paper, the antitumor activity and structure-bioactivity relationships of plant polysaccharides are systematically summarized to provide a reference for discovering its new breakthroughs and further development.http://www.spgykj.com/cn/article/doi/10.13386/j.issn1002-0306.2022050063plant polysaccharidesanti-tumormechanism of actionstructure-activity relationship
spellingShingle Guifeng ZHANG
Chuang LIU
Guangdong LIU
Rentang ZHANG
Research Progress on Antitumor Mechanism and Structure-activity Relationship of Plant Polysaccharides
Shipin gongye ke-ji
plant polysaccharides
anti-tumor
mechanism of action
structure-activity relationship
title Research Progress on Antitumor Mechanism and Structure-activity Relationship of Plant Polysaccharides
title_full Research Progress on Antitumor Mechanism and Structure-activity Relationship of Plant Polysaccharides
title_fullStr Research Progress on Antitumor Mechanism and Structure-activity Relationship of Plant Polysaccharides
title_full_unstemmed Research Progress on Antitumor Mechanism and Structure-activity Relationship of Plant Polysaccharides
title_short Research Progress on Antitumor Mechanism and Structure-activity Relationship of Plant Polysaccharides
title_sort research progress on antitumor mechanism and structure activity relationship of plant polysaccharides
topic plant polysaccharides
anti-tumor
mechanism of action
structure-activity relationship
url http://www.spgykj.com/cn/article/doi/10.13386/j.issn1002-0306.2022050063
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AT chuangliu researchprogressonantitumormechanismandstructureactivityrelationshipofplantpolysaccharides
AT guangdongliu researchprogressonantitumormechanismandstructureactivityrelationshipofplantpolysaccharides
AT rentangzhang researchprogressonantitumormechanismandstructureactivityrelationshipofplantpolysaccharides