High Frequency Ultrasound of Basal Cell Carcinomas: Ultrasonographic Features and Histological Subtypes, a Retrospective Study of 100 Tumors
(1) Background: 22 MHz high frequency ultrasound (HFUS) is a non-invasive imaging technique that gives information on depth, length, volume and shape of skin tumors. (2) Methods: We reviewed the clinical, ultrasound, and histological records of 54 patients with 100 histologically confirmed basal cel...
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| Format: | Article |
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MDPI AG
2023-06-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/12/12/3893 |
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| author | Styliani Siskou Paola Pasquali Myrto Trakatelli |
| author_facet | Styliani Siskou Paola Pasquali Myrto Trakatelli |
| author_sort | Styliani Siskou |
| collection | DOAJ |
| description | (1) Background: 22 MHz high frequency ultrasound (HFUS) is a non-invasive imaging technique that gives information on depth, length, volume and shape of skin tumors. (2) Methods: We reviewed the clinical, ultrasound, and histological records of 54 patients with 100 histologically confirmed basal cell carcinoma (BCC) tumors with the use of HFUS. (3) Results: Most infiltrative tumors (<i>n</i> = 16/21, 76.2%) were irregular shaped, followed by five (23.8%) being round shaped; most superficial tumors (<i>n</i> = 25/29, 86.2%) were ribbon shaped, followed by four (13.8%) being round shaped; most nodular tumors (<i>n</i> = 26/33, 78.8%) were round shaped, followed by seven (21.2%) that were irregular shaped; and, lastly, all microdular tumors (<i>n</i> = 2/2, 100%) were round shaped. Strong evidence of association (<i>p</i> = 0.000) was observed between the histological subtype and tumor shape as seen using the HFUS. No evidence of association was found between the histological subtype and tumor margin (<i>p</i> > 0.005). Cohen’s Kappa statistic to assess the agreement between BCC subtypes evaluated by histological examination and U/S appearance was calculated equal to 0.8251 (almost perfect agreement). (4) Conclusions: HFUS appears to be a reliable technique for the pre-operative evaluation of BCCs, assisting physicians to decide on the optimal therapeutic approach. |
| first_indexed | 2024-03-11T02:19:03Z |
| format | Article |
| id | doaj.art-0fd90c0150b04be3826de53d48a6a3da |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-11T02:19:03Z |
| publishDate | 2023-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-0fd90c0150b04be3826de53d48a6a3da2023-11-18T10:58:08ZengMDPI AGJournal of Clinical Medicine2077-03832023-06-011212389310.3390/jcm12123893High Frequency Ultrasound of Basal Cell Carcinomas: Ultrasonographic Features and Histological Subtypes, a Retrospective Study of 100 TumorsStyliani Siskou0Paola Pasquali1Myrto Trakatelli2Second Dermatology Department, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, GreeceDermatology Department, Pius Hospital de Valls, Universidad de Alacalá, 43800 Valls, SpainSecond Dermatology Department, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece(1) Background: 22 MHz high frequency ultrasound (HFUS) is a non-invasive imaging technique that gives information on depth, length, volume and shape of skin tumors. (2) Methods: We reviewed the clinical, ultrasound, and histological records of 54 patients with 100 histologically confirmed basal cell carcinoma (BCC) tumors with the use of HFUS. (3) Results: Most infiltrative tumors (<i>n</i> = 16/21, 76.2%) were irregular shaped, followed by five (23.8%) being round shaped; most superficial tumors (<i>n</i> = 25/29, 86.2%) were ribbon shaped, followed by four (13.8%) being round shaped; most nodular tumors (<i>n</i> = 26/33, 78.8%) were round shaped, followed by seven (21.2%) that were irregular shaped; and, lastly, all microdular tumors (<i>n</i> = 2/2, 100%) were round shaped. Strong evidence of association (<i>p</i> = 0.000) was observed between the histological subtype and tumor shape as seen using the HFUS. No evidence of association was found between the histological subtype and tumor margin (<i>p</i> > 0.005). Cohen’s Kappa statistic to assess the agreement between BCC subtypes evaluated by histological examination and U/S appearance was calculated equal to 0.8251 (almost perfect agreement). (4) Conclusions: HFUS appears to be a reliable technique for the pre-operative evaluation of BCCs, assisting physicians to decide on the optimal therapeutic approach.https://www.mdpi.com/2077-0383/12/12/3893high frequency ultrasoundbasal cell carcinomahistology subtypenon-invasive imaging techniquesultrasound |
| spellingShingle | Styliani Siskou Paola Pasquali Myrto Trakatelli High Frequency Ultrasound of Basal Cell Carcinomas: Ultrasonographic Features and Histological Subtypes, a Retrospective Study of 100 Tumors Journal of Clinical Medicine high frequency ultrasound basal cell carcinoma histology subtype non-invasive imaging techniques ultrasound |
| title | High Frequency Ultrasound of Basal Cell Carcinomas: Ultrasonographic Features and Histological Subtypes, a Retrospective Study of 100 Tumors |
| title_full | High Frequency Ultrasound of Basal Cell Carcinomas: Ultrasonographic Features and Histological Subtypes, a Retrospective Study of 100 Tumors |
| title_fullStr | High Frequency Ultrasound of Basal Cell Carcinomas: Ultrasonographic Features and Histological Subtypes, a Retrospective Study of 100 Tumors |
| title_full_unstemmed | High Frequency Ultrasound of Basal Cell Carcinomas: Ultrasonographic Features and Histological Subtypes, a Retrospective Study of 100 Tumors |
| title_short | High Frequency Ultrasound of Basal Cell Carcinomas: Ultrasonographic Features and Histological Subtypes, a Retrospective Study of 100 Tumors |
| title_sort | high frequency ultrasound of basal cell carcinomas ultrasonographic features and histological subtypes a retrospective study of 100 tumors |
| topic | high frequency ultrasound basal cell carcinoma histology subtype non-invasive imaging techniques ultrasound |
| url | https://www.mdpi.com/2077-0383/12/12/3893 |
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