A Simple LC-MS/MS Method for the Quantification of PDA-66 in Human Plasma

A Simple LC-MS/MS Method for the Quantification of PDA-66 in Human Plasma

The treatment of cancer is one of the most important pharmacotherapeutic challenges. To this end, chemotherapy has for some time been complemented by targeted therapies against specific structures. PDA-66, a structural analogue of the inhibitor of serine–threonine kinase glycogen synthase kinase 3β...

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Bibliographic Details
Main Authors: Rico Schwarz, Elisabeth R. D. Seiler, Sina Sender, Anahit Pews-Davtyan, Hugo Murua Escobar, Dietmar Zechner, Matthias Beller, Christian Junghanß, Burkhard Hinz
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Molecules
Subjects:
PDA-66
human plasma
LC-MS/MS
validation
liquid–liquid extraction
Online Access:https://www.mdpi.com/1420-3049/27/3/974

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