Functional characteristics of Th1, Th17, and ex-Th17 cells in EAE revealed by intravital two-photon microscopy

Functional characteristics of Th1, Th17, and ex-Th17 cells in EAE revealed by intravital two-photon microscopy

Abstract Background T helper (Th) 17 cells are a highly plastic subset of T cells, which in the context of neuroinflammation, are able to acquire pathogenic features originally attributed to Th1 cells (resulting in so called ex-Th17 cells). Thus, a strict separation between the two T cell subsets in...

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Bibliographic Details
Main Authors: Julia Loos, Samantha Schmaul, Theresa Marie Noll, Magdalena Paterka, Miriam Schillner, Julian T. Löffel, Frauke Zipp, Stefan Bittner
Format: Article
Language:English
Published: BMC 2020-11-01
Series:Journal of Neuroinflammation
Subjects:
EAE
Th1 cells
Th17 cells
Two-photon microscopy
Online Access:https://doi.org/10.1186/s12974-020-02021-x

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