IQGAP1 is an oncogenic target in canine melanoma.

IQGAP1 is an oncogenic target in canine melanoma.

Canine oral mucosal melanoma is an aggressive malignant neoplasm and is characterized by local infiltration and a high metastatic potential. The disease progression is similar to that of human oral melanomas. Whereas human cutaneous melanoma is primarily driven by activating mutations in Braf (60%)...

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Bibliographic Details
Main Authors: Becky H Lee, Poornima H Neela, Michael S Kent, Ashley M Zehnder
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5406000?pdf=render

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