YB‐1 regulates mesothelioma cell migration via snail but not EGFR, MMP1, EPHA5 or PARK2

YB‐1 regulates mesothelioma cell migration via snail but not EGFR, MMP1, EPHA5 or PARK2

Pleural mesothelioma (PM) is characterized by rapid growth, local invasion, and limited therapeutic options. The multifunctional oncoprotein Y‐box‐binding protein‐1 (YB‐1) is frequently overexpressed in cancer and its inhibition reduces aggressive behavior in multiple tumor types. Here, we investiga...

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Bibliographic Details
Main Authors: Karin Schelch, Sebastian Eder, Benjamin Zitta, Monica Phimmachanh, Thomas G. Johnson, Dominik Emminger, Andrea Wenninger‐Weinzierl, Caterina Sturtzel, Hugo Poplimont, Alexander Ries, Konrad Hoetzenecker, Mir A. Hoda, Walter Berger, Martin Distel, Balazs Dome, Glen Reid, Michael Grusch
Format: Article
Language:English
Published: Wiley 2024-04-01
Series:Molecular Oncology
Subjects:
cell migration
EGFR
pleural mesothelioma
snail
YB‐1
Online Access:https://doi.org/10.1002/1878-0261.13367

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