Metabolic impact of anti-angiogenic agents on U87 glioma cells.

Metabolic impact of anti-angiogenic agents on U87 glioma cells.

BACKGROUND: Glioma cells not only secrete high levels of vascular endothelial growth factor (VEGF) but also express VEGF receptors (VEGFR), supporting the existence of an autocrine loop. The direct impact on glioma cells metabolism of drugs targeting the VEGF pathway, such as Bevacizumab (Bev) or VE...

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Bibliographic Details
Main Authors: Tanja Mesti, Philippe Savarin, Mohamed N Triba, Laurence Le Moyec, Janja Ocvirk, Claire Banissi, Antoine F Carpentier
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4055646?pdf=render

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