May the Force Be with You (Or Not): The Immune System under Microgravity
All terrestrial organisms have evolved and adapted to thrive under Earth’s gravitational force. Due to the increase of crewed space flights in recent years, it is vital to understand how the lack of gravitational forces affects organisms. It is known that astronauts who have been exposed to microgra...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-07-01
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| Series: | Cells |
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| Online Access: | https://www.mdpi.com/2073-4409/10/8/1941 |
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| author | Mei ElGindi Jiranuwat Sapudom Ibrahim Hamed Ibrahim Mohamed Al-Sayegh Weiqiang Chen Anna Garcia-Sabaté Jeremy C. M. Teo |
| author_facet | Mei ElGindi Jiranuwat Sapudom Ibrahim Hamed Ibrahim Mohamed Al-Sayegh Weiqiang Chen Anna Garcia-Sabaté Jeremy C. M. Teo |
| author_sort | Mei ElGindi |
| collection | DOAJ |
| description | All terrestrial organisms have evolved and adapted to thrive under Earth’s gravitational force. Due to the increase of crewed space flights in recent years, it is vital to understand how the lack of gravitational forces affects organisms. It is known that astronauts who have been exposed to microgravity suffer from an array of pathological conditions including an impaired immune system, which is one of the most negatively affected by microgravity. However, at the cellular level a gap in knowledge exists, limiting our ability to understand immune impairment in space. This review highlights the most significant work done over the past 10 years detailing the effects of microgravity on cellular aspects of the immune system. |
| first_indexed | 2024-03-10T08:55:10Z |
| format | Article |
| id | doaj.art-0fde584100234d95bc8003e883474ac5 |
| institution | Directory Open Access Journal |
| issn | 2073-4409 |
| language | English |
| last_indexed | 2024-03-10T08:55:10Z |
| publishDate | 2021-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cells |
| spelling | doaj.art-0fde584100234d95bc8003e883474ac52023-11-22T07:09:28ZengMDPI AGCells2073-44092021-07-01108194110.3390/cells10081941May the Force Be with You (Or Not): The Immune System under MicrogravityMei ElGindi0Jiranuwat Sapudom1Ibrahim Hamed Ibrahim2Mohamed Al-Sayegh3Weiqiang Chen4Anna Garcia-Sabaté5Jeremy C. M. Teo6Laboratory for Immuno Bioengineering Research and Applications, Division of Engineering, New York University Abu Dhabi, Abu Dhabi P.O. Box 129188, United Arab EmiratesLaboratory for Immuno Bioengineering Research and Applications, Division of Engineering, New York University Abu Dhabi, Abu Dhabi P.O. Box 129188, United Arab EmiratesLaboratory for Immuno Bioengineering Research and Applications, Division of Engineering, New York University Abu Dhabi, Abu Dhabi P.O. Box 129188, United Arab EmiratesBiology Division, New York University Abu Dhabi, Abu Dhabi P.O. Box 129188, United Arab EmiratesDepartment of Mechanical and Aerospace Engineering, New York University, Brooklyn, NY 11201, USALaboratory for Immuno Bioengineering Research and Applications, Division of Engineering, New York University Abu Dhabi, Abu Dhabi P.O. Box 129188, United Arab EmiratesLaboratory for Immuno Bioengineering Research and Applications, Division of Engineering, New York University Abu Dhabi, Abu Dhabi P.O. Box 129188, United Arab EmiratesAll terrestrial organisms have evolved and adapted to thrive under Earth’s gravitational force. Due to the increase of crewed space flights in recent years, it is vital to understand how the lack of gravitational forces affects organisms. It is known that astronauts who have been exposed to microgravity suffer from an array of pathological conditions including an impaired immune system, which is one of the most negatively affected by microgravity. However, at the cellular level a gap in knowledge exists, limiting our ability to understand immune impairment in space. This review highlights the most significant work done over the past 10 years detailing the effects of microgravity on cellular aspects of the immune system.https://www.mdpi.com/2073-4409/10/8/1941immune cellsimmunologymicrogravityspace researchspace biologymechanotransduction |
| spellingShingle | Mei ElGindi Jiranuwat Sapudom Ibrahim Hamed Ibrahim Mohamed Al-Sayegh Weiqiang Chen Anna Garcia-Sabaté Jeremy C. M. Teo May the Force Be with You (Or Not): The Immune System under Microgravity Cells immune cells immunology microgravity space research space biology mechanotransduction |
| title | May the Force Be with You (Or Not): The Immune System under Microgravity |
| title_full | May the Force Be with You (Or Not): The Immune System under Microgravity |
| title_fullStr | May the Force Be with You (Or Not): The Immune System under Microgravity |
| title_full_unstemmed | May the Force Be with You (Or Not): The Immune System under Microgravity |
| title_short | May the Force Be with You (Or Not): The Immune System under Microgravity |
| title_sort | may the force be with you or not the immune system under microgravity |
| topic | immune cells immunology microgravity space research space biology mechanotransduction |
| url | https://www.mdpi.com/2073-4409/10/8/1941 |
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